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Serum or plasma mass concentration of C-reactive protein (CRP)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of C-reactive protein in your blood, a protein produced by your liver in response to inflammation.

Quick summary

["CRP helps doctors assess inflammation in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4503-9
Short code
C4BP
Synonyms
C4b BP SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or plain red-top tube
Units
N/A
Ref low
0.18
Ref high
0.55
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA) or nephelometry
Specimen volume
1 mL serum
Stability
Stable for 8 hours at room temperature, 2 days at 2–8°C, or 3 months at -20°C
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What Is C-Reactive Protein (CRP)?

C-reactive protein (CRP) is a marker your immune system produces when tissues are damaged or inflamed. It’s often measured to check for infections, autoimmune conditions, or other inflammatory processes. CRP isn’t specific to any single condition—it’s a general indicator of your body’s inflammatory response.

Why Might You Need This Test?

Your doctor may order CRP testing to monitor chronic conditions like arthritis, heart disease, or inflammatory bowel disease. It can also help track how well treatments are working or detect new inflammation after surgery, injury, or illness. In some cases, it’s used as part of a broader screening for cardiovascular risk.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure CRP levels. The test is quick and typically done as part of a routine blood draw.

What Do Results Mean?

Results are usually reported in milligrams per liter (mg/L). Higher levels may suggest inflammation, infection, or other underlying issues, but interpretation depends on your overall health and symptoms. Your doctor will discuss the results with you.

Reference range

0.18–0.55 g/L (varies by laboratory and assay method)N/A

Specimen: serum

No special patient preparation required. Specimen should be collected before any immunosuppressive therapy when possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP Level

Frequently asked questions

How often do I need this test?
CRP levels can vary depending on your health status, recent infections, or medications. Your doctor will determine how often to retest based on your condition and medical history. For example, people with chronic inflammatory diseases may need regular monitoring.
What happens if my CRP levels are high?
High CRP levels can signal inflammation, but they don’t always point to a specific problem. Your doctor may recommend further tests or treatments to address the underlying cause. In some cases, lifestyle changes or medications can help reduce inflammation.
Can I influence my CRP levels?
Yes! Factors like diet (e.g., reducing processed foods and sugar), exercise, stress management, and smoking can lower CRP levels. Ask your doctor about strategies tailored to your situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy