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Serum or plasma mass concentration of calcium

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium in your blood, which is important for many body functions, including muscle and nerve activity, as well as bone health.

Quick summary

["Checks calcium levels to prevent deficiencies or excesses that could affect your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
26931-6
Short code
C4
Synonyms
C4 SerPl-aCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube; plasma acceptable in heparin or EDTA tubes
Units
N/A
Ref low
10
Ref high
40
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunonephelometry or Immunoturbidimetry
CPT
86160
SNOMED
71878006
Specimen volume
1 mL serum or plasma
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 2 days; Frozen (-20°C or below): 30 days
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like muscle cramps, numbness, fatigue, or bone pain. It may also be done to monitor conditions like kidney disease, osteoporosis, or certain metabolic disorders. Sometimes, it’s part of routine check-ups or to evaluate calcium-related medications.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s a fasting sample. If you’re on calcium supplements or certain medications, let your provider know. Avoid drinking calcium-rich beverages like milk or juice before the test if instructed.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The blood will be sent to a lab for analysis.

What Does the Test Result Mean?

Results are compared to standard ranges, but your specific reference values may vary based on lab methods and your healthcare provider’s guidelines. Low calcium levels (hypocalcemia) can cause weakness or spasms, while high levels (hypercalcemia) may lead to fatigue or kidney issues. Your provider will discuss results with you in detail.

Reference range

Adults: 10-40 mg/dL (may vary by laboratory and assay method)N/A

Specimen: serum

No special preparation required. Fasting is not necessary.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Calcium Level

Frequently asked questions

How often do I need this test?
The frequency depends on your health status. Routine adults may not need it unless they have risk factors (e.g., kidney disease, thyroid issues, or recent surgery). Children or those with bone disorders may need it more often. Follow your provider’s advice.
Can I eat or drink anything before the test?
If fasting is required, avoid food and liquids (except water) for 8–12 hours before drawing blood. If not fasting, eat a normal meal. Always check with your provider for specific instructions.
What if my calcium level is too high or too low?
If your results are outside normal ranges, your provider may recommend further tests or treatments, such as adjusting medications, dietary changes, or monitoring for underlying conditions like vitamin D deficiency or kidney problems. Never self-treat without guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy