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Bilirubin Crystals, Qualitative, Urine

Published: August 9, 2026Updated: August 16, 2026

A urine microscopy test that identifies bilirubin crystals in a urine sample. It may be used when excess bilirubin or liver-related conditions are being evaluated.

Quick summary

["Detects bilirubin crystals in urine, which can occur when bilirubin levels are unusually high."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16261-0
Short code
Ca Bilirub Cry Stone Ql IR
Synonyms
Ca Bilirub Cry Stone Ql IR
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
infrared-spectroscopy
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test examines a urine sample for bilirubin crystals. Bilirubin is a yellow pigment produced when the body breaks down red blood cells and is normally processed by the liver.

Why might I need this test?

This test may be ordered if another urine test shows unusually high bilirubin, or if a clinician is evaluating liver disease, bile duct obstruction, or other causes of increased bilirubin.

How is the test performed?

A urine sample is collected and examined under a microscope to identify the characteristic appearance of bilirubin crystals. The result is reported as present or absent.

How do I prepare for the test?

Follow your clinician's instructions for collecting the urine sample, often using a clean-catch midstream sample. Tell the laboratory if you are taking medicines or have recently had antibiotics, as these may affect urine findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Bilirubin crystals may be found when the amount of bilirubin in the urine is greatly increased. This can occur with liver injury, impaired bile flow or bile duct obstruction, and certain blood disorders. The finding should be interpreted with the rest of your liver and urine test results.

Short name

Urine bilirubin crystals

Frequently asked questions

What does a positive result mean?
A positive result means bilirubin crystals were identified in the urine. This often suggests that the urine contains an unusually high concentration of bilirubin, but other clinical information is needed to determine the cause.
Does finding bilirubin crystals mean I have liver disease?
Not necessarily. Bilirubin crystals can accompany several conditions that increase bilirubin, including liver disease and bile duct obstruction, so your clinician will interpret the result alongside your symptoms and other tests.
Is this the same as a routine urine bilirubin dipstick test?
No. A dipstick estimates the amount of bilirubin in urine using a color reaction, while this test identifies actual bilirubin crystals by examining the urine under a microscope.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy