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Cadmium concentration in whole blood

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of cadmium in a sample of whole blood. It can help assess recent or ongoing exposure to cadmium, particularly from workplace or environmental sources.

Quick summary

["An elevated result may indicate exposure to cadmium and should be interpreted by a healthcare professional in the context of your symptoms, history, and other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
15117-5
Short code
CDBL
Synonyms
Cadmium Bld-sCnc
Category
chemistry
Sample
whole-blood
Container
Royal blue-top (EDTA) trace element blood collection tube
Units
N/A
Ref low
20
Ref high
35
Critical range
— – 90 N/A
Fasting
false
Population
adult
Sex
all
Age range
1–99 years
Method
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
CPT
82300
SNOMED
271324002
Specimen volume
3 mL whole blood
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 30 days; Frozen (-20°C): 1 year. Mix tube gently before aliquoting.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–96 hours
Order
routine

What this test measures

Cadmium is a naturally occurring metal that can enter the body through breathing, drinking, or eating. This test measures cadmium in whole blood rather than in a urine sample.

Why it may be ordered

A clinician may order this test after possible exposure to cadmium, such as in battery, metal smelting, welding, or manufacturing work. It may also be used when symptoms raise concern about metal exposure.

How the test is performed

A blood sample is collected through a needle in a vein. The specimen is then analyzed in a laboratory, and the result is reported as a cadmium concentration.

Factors that may affect the result

Recent exposure, smoking, diet, kidney function, and laboratory measurement methods can influence blood cadmium levels. Test results should therefore be interpreted alongside occupational and environmental history.

Reference range

Reference values for blood cadmium in non-smoking adults are typically < 5.0 nmol/L (< 0.5 µg/L). Smokers may have elevated baseline levels up to 20-35 nmol/L due to tobacco exposure. Occupational exposure limits: OSHA PEL 5 µg/L (44.5 nmol/L); ACGIH Biological Exposure Index 5 µg/L.N/A

Specimen: whole-blood

No fasting required. Patients should refrain from consuming shellfish or other cadmium-rich foods for 48 hours prior to collection if monitoring for occupational exposure. Avoid collection immediately after smoking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Blood cadmium can provide information about cadmium exposure, but it does not by itself identify the source of exposure or establish that a specific illness is present. Abnormal results may lead to further evaluation, including review of symptoms, exposure history, kidney function tests, and other appropriate studies.

Short name

Whole-blood cadmium level

Frequently asked questions

Does a high result mean cadmium poisoning?
A high result suggests that cadmium exposure may be increased, but it must be interpreted with symptoms, exposure history, and other clinical information. Your clinician can determine whether further evaluation or action is needed.
How long does cadmium remain detectable in blood?
Blood reflects relatively recent exposure, but the exact interpretation depends on the exposure pattern and individual factors. Your clinician can explain what the result means for your situation.
Do I need to prepare for this test?
You generally do not need to stop medications or fast unless your clinician specifically instructs you to do so. Inform the healthcare team and laboratory about any recent metal exposure, occupational work, supplements, or relevant medical conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy