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###1: Cadmium, Serum/Plasma Substance Concentration

Published: August 9, 2026Updated: August 15, 2026

###3: This test measures the amount of cadmium in a blood sample. Cadmium is a toxic metal that can enter the body through environmental or occupational exposure.

Quick summary

["###4: The result helps assess recent cadmium exposure and whether further evaluation or exposure reduction is needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
25359-1
Short code
CD-S
Synonyms
Cadmium SerPl-sCnc
Category
chemistry
Sample
serum
Container
Royal blue-top (trace element) evacuated tube; alternatively, dark blue-top sodium heparin tube for plasma
Units
N/A
Ref low
0
Ref high
5
Critical range
— – 50 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–99 years
Method
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
CPT
82300
SNOMED
395071000009108
Specimen volume
2 mL serum or plasma
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 6 months
Hemolysis max
50
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

###5: What Does the Test Measure?

###6: The test measures cadmium dissolved in serum or plasma, the liquid portion of blood. It is used to evaluate exposure to cadmium, which can accumulate in the body over time.

###7: Why Is This Test Ordered?

###8: This test may be ordered for people with possible exposure to cadmium in workplaces, contaminated water, soil, food, or industrial processes. It may also be used to monitor certain occupational exposure situations.

###9: How Should I Prepare?

###10: Follow the laboratory’s preparation instructions. Your healthcare professional should tell you whether to avoid food, drinks, medications, supplements, or recent occupational exposure before the sample is collected.

###11: How Are the Results Interpreted?

###11: Results are interpreted according to the laboratory’s established method and reference interval. A higher result may suggest increased exposure, but the result should be considered along with exposure history, symptoms, and other tests.

Reference range

Non-exposed adults: <5.0 nmol/L; Occupational exposure (BEI): <45 nmol/LN/A

Specimen: serum

No fasting required. Patient should avoid recent seafood consumption (shellfish) for 48 hours prior to collection as it may elevate cadmium levels. Avoid smoking for at least 24 hours before specimen collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

###13: Cadmium is a toxic metal, so an elevated result may indicate recent or ongoing exposure and can prompt review of the exposure source. A result does not by itself show which organs are affected; additional testing may be needed depending on the clinical situation.

Short name

###2: Serum/Plasma Cadmium

Frequently asked questions

###14: Is this the same as a urine cadmium test?
###15: No. A blood cadmium test reflects cadmium in the circulating serum or plasma and is generally used to assess more recent exposure. A urine test measures cadmium excreted in urine and may be used to evaluate ongoing exposure over a longer period.
###16: Does an abnormal result mean I have cadmium poisoning?
###17: Not necessarily. An abnormal result can suggest exposure, but it must be interpreted with the laboratory’s reference interval, exposure history, and your symptoms. A clinician can determine whether additional evaluation or treatment is appropriate.
###18: What should I do if my result is high?
###19: Contact your healthcare professional or occupational health provider promptly. They can review your exposure, recommend ways to reduce exposure, and decide whether repeat testing or tests of organ function are needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy