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: Cadmium [Mass or Content] in Tissue by Mass Concentration Measurement

Published: August 9, 2026Updated: August 16, 2026

: This test measures the amount of cadmium present in a tissue sample. Cadmium is a toxic metal that can accumulate in the body over time, and tissue measurement helps assess exposure or body burden.

Quick summary

[": A tissue cadmium measurement estimates how much of this harmful metal has built up in body tissue, which can inform exposure assessment and clinical follow-up."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20737-3
Short code
CDTM
Synonyms
Cadmium Tiss-mCnt
Category
chemistry
Sample
serum
Container
Cadmium-free trace element collection tube (royal blue top EDTA or sodium heparin) for serum; metal-free cryogenic container for tissue specimens
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Graphite Furnace Atomic Absorption Spectrometry (GFAAS)
CPT
82300
SNOMED
39562008
Specimen volume
1 mL serum; minimum 0.5 g tissue
Stability
Serum: 7 days at 2-8°C; 6 months at -20°C. Tissue: indefinite at -70°C or below in metal-free containers
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
48–168 hours
Order
routine

: What Is Being Measured

: Cadmium is a naturally occurring metal found in small amounts in soil, water, and air, and also in cigarette smoke and some industrial workplaces. The body does not clear cadmium efficiently, so repeated exposure can lead to accumulation, especially in organs such as the kidneys and liver. This test detects and quantifies cadmium in a tissue specimen.

: Why the Test May Be Ordered

: A healthcare provider may order tissue cadmium testing when there is concern about significant exposure, such as occupational contact, smoking history, or known environmental exposure. It is one part of a broader evaluation and is usually interpreted together with other tests and a detailed exposure history.

: How the Sample Is Collected

: Because the slug indicates a tissue measurement, the specimen is a tissue sample rather than blood or urine. The exact collection method depends on the clinical setting and the provider's request, and a trained professional obtains and prepares the sample according to laboratory instructions.

: What Results Can Mean

: Results indicate the amount of cadmium detected in the tissue sample relative to the laboratory's reporting method. Higher levels generally suggest greater accumulation or exposure, but results must be interpreted by a clinician in the context of symptoms, exposure history, and other laboratory findings. This test does not by itself diagnose a specific disease.

Reference range

Reference ranges vary by tissue type; non-occupationally exposed individuals typically have cadmium levels below 1 μg/g in renal cortex. Consult laboratory-specific reference values for tissue-specific ranges.N/A

Specimen: serum

No special preparation required for serum specimen. For tissue biopsy specimens, document tissue source, collection site, and time of collection. Avoid contamination by using cadmium-free collection instruments.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: Tissue Cadmium

Frequently asked questions

: Is this the same as a blood or urine cadmium test?
: No. This test measures cadmium in a tissue sample, which is different from measuring cadmium in blood or urine. Each specimen type provides different information, and your provider will choose the test appropriate for your situation.
: Can I prepare for this test on my own?
: Preparation depends on the specific procedure used to obtain the tissue sample. Follow the instructions given by your healthcare provider and the collecting facility; do not make assumptions about fasting or other preparation without guidance.
: Do high cadmium levels always mean I will have health problems?
: Not necessarily. Results reflect the amount measured in the sample and must be interpreted along with your exposure history, symptoms, and other tests. Only your healthcare provider can determine what the result means for your health and whether follow-up is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy