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Cadmium in Urine (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cadmium, a heavy metal, present in your urine over a 24-hour period. Cadmium exposure can occur from environmental sources like contaminated air or water, or from certain foods.

Quick summary

["Urine cadmium testing helps identify potential exposure to harmful metals."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25360-9
Short code
CD-U
Synonyms
Cadmium Ur-sCnc
Category
chemistry
Sample
urine
Container
Acid-washed trace element-free polyethylene urine container; royal blue-top vacutainer (no additive)
Units
N/A
Ref low
0
Ref high
1
Critical range
— – 100 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
CPT
82300
SNOMED
707801000
Specimen volume
10-50 mL of random or 24-hour urine collection
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C): 1 year. Acidify to pH <2 with concentrated nitric acid for long-term storage.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–72 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of metal poisoning, such as nausea, vomiting, or kidney problems, or if you work in an industry with known cadmium exposure (e.g., mining, battery manufacturing). They might also order it as part of a general health check or if you’ve been exposed to environmental toxins.

What to Expect Before the Test

No special preparation is usually needed, but you’ll need to collect all urine produced in a 24-hour period (typically from one morning to the next morning). Follow your healthcare provider’s instructions carefully to ensure accurate results.

What the Test Results Mean

Higher-than-normal levels of cadmium in urine can indicate recent exposure to this metal. Elevated levels may raise concerns about potential long-term health effects, such as kidney damage or other organ toxicity, though further evaluation would be needed.

Common Causes of Elevated Levels

Elevated urine cadmium levels can result from occupational exposure (e.g., to cigarette smoke, industrial dust, or contaminated water). It may also appear after accidental ingestion of cadmium-containing products or from long-term dietary exposure to foods grown in cadmium-contaminated soil.

Reference range

Non-exposed adult population: <1.0 µg/g creatinine (or <1.0 µg/L for spot urine). Occupational exposure (BEI): <5.0 µg/g creatinine. Values may vary by laboratory and reference population.N/A

Specimen: urine

No fasting required. Patients should avoid shellfish and seafood consumption for 48 hours prior to collection. Avoid smoking, as tobacco is a major source of cadmium exposure. Use of chelating agents should be noted.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Urine Cadmium

Frequently asked questions

What does a high urine cadmium level suggest?
A high urine cadmium level suggests recent or ongoing exposure to cadmium, which can be harmful to organs like the kidneys. It may indicate occupational hazards, environmental contamination, or other sources of exposure. Your healthcare provider will assess the results in the context of your medical history and symptoms to guide further action.
What does a normal urine cadmium level mean?
A normal urine cadmium level means there is no detectable recent exposure to cadmium in your urine, but it does not guarantee you are not at risk from past exposure or long-term effects. If you suspect exposure, discuss it with your provider.
Can diet affect urine cadmium levels?
Yes, diet can influence urine cadmium levels. Certain foods, such as shellfish, leafy greens, and some grains, may contain cadmium. However, the impact of diet alone on urine cadmium levels is usually minimal unless you have a history of heavy metal exposure or dietary habits that consistently expose you to cadmium.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy