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Cadmium in Urine (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of cadmium, a heavy metal, found in your urine over a 24-hour period. Cadmium exposure can occur from environmental sources or certain industrial activities.

Quick summary

["Cadmium levels in urine help identify potential exposure to this harmful substance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34255-0
Short code
UCD
Synonyms
Cadmium Ur-sRate
Category
chemistry
Sample
urine
Container
Trace element-free polyethylene urine container; acid-washed preferred
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
CPT
82300
SNOMED
313835004
Specimen volume
10-50 mL random or 24-hour urine collection
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C): 6 months. Acidify to pH <2 with nitric acid for long-term storage.
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–72 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms of heavy metal poisoning, such as nausea, vomiting, or kidney problems, or if you work in an environment with potential cadmium exposure (e.g., mining, manufacturing). They might also recommend it if you have a history of chronic kidney disease or other health conditions linked to metal toxicity.

What to Expect Before the Test

No special preparation is needed for this test. You’ll collect your urine over a full 24-hour period, starting right after you wake up and ending just before you wake up the next morning. Store the urine in a clean container and bring it to your lab visit.

What to Expect During the Test

The test involves collecting all urine produced during a 24-hour period. You’ll need to measure and record each time you urinate, keeping the urine in a container until the test is complete. Some labs may provide a 24-hour urine collection kit to simplify the process.

What the Results Mean

Higher than expected levels of cadmium in urine may indicate recent exposure to cadmium or an ongoing health concern. Your healthcare provider will interpret the results in relation to your medical history and other tests.

Reference range

Non-exposed adults: <1.0 µg/g creatinine (typically <0.8 µg/24h); OSHA biological exposure limit: <5 µg/g creatinineN/A

Specimen: urine

No fasting required. Avoid shellfish and cadmium-containing foods for 48 hours prior to collection. Refrain from smoking for at least 24 hours before collection as tobacco contains cadmium.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Cadmium

Frequently asked questions

What causes elevated cadmium levels in urine?
Elevated cadmium levels can result from occupational exposure (e.g., working in industries like mining, welding, or battery manufacturing), smoking, or environmental contamination. Certain foods, like shellfish, may also contain small amounts. Chronic kidney disease or genetic factors can sometimes contribute.
What symptoms might I experience if cadmium levels are high?
Symptoms of high cadmium exposure may include nausea, vomiting, stomach pain, kidney problems (like reduced urine output), weakness, or bone pain. Some people may not show symptoms until long-term exposure occurs.
How is cadmium exposure managed or prevented?
If exposure is suspected, your doctor may recommend reducing contact with cadmium sources, following workplace safety guidelines, or switching to less hazardous jobs. Dietary changes (e.g., limiting shellfish) and avoiding smoking may also help. Regular monitoring of cadmium levels can guide ongoing care.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy