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Candida albicans quantitative culture from cerebrospinal fluid

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of *Candida albicans*, a type of yeast, in your cerebrospinal fluid (CSF). It helps determine if an infection (meningitis or another brain/spinal cord infection) is caused by this fungus.

Quick summary

["Identifies potential fungal infection in your nervous system fluids."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33461-5
Short code
CANDAB
Synonyms
C albicans Ab CSF Ql
Category
chemistry
Sample
csf
Container
Sterile, leak-proof, screw-cap polypropylene cryovial or conical tube; sterile CSF collection tubes
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Enzyme Immunoassay (EIA) or Immunofluorescence Assay (IFA) for detection of Candida albicans antibodies in cerebrospinal fluid
CPT
86628
SNOMED
122460008
Specimen volume
1-2 mL of cerebrospinal fluid
Stability
Refrigerated (2-8°C): up to 7 days; Frozen (-20°C or lower): up to 4 weeks; Avoid repeated freeze-thaw cycles
Hemolysis max
200
TAT
24–72 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, fever, confusion, or neurological issues that could suggest meningitis or another brain/spinal cord infection. It’s also used in monitoring patients with weakened immune systems or those who’ve received treatments that lower immunity.

How the Test Works

A small sample of your CSF is collected via a procedure called a lumbar puncture (spinal tap). The sample is then sent to a lab where it’s cultured to grow any yeast (like *Candida albicans*) over time. If the yeast grows, it confirms the presence of infection.

Sample Collection & Preparation

The procedure involves inserting a needle into your lower back to collect CSF. You may feel pressure or mild discomfort, but it’s usually quick. The sample is immediately sent to the lab for culture, which can take days to weeks to produce results.

What to Expect Before or After

No special preparation is needed. After the procedure, you may experience mild soreness or headache, which can be managed with rest and over-the-counter pain relievers. Avoid strenuous activity for 24 hours.

Reference range

Negative (No Candida albicans antibodies detected)N/A

Specimen: csf

No special patient preparation required. Inform the ordering physician of any current antifungal therapy, recent antibiotic use, or immunocompromised status prior to specimen collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Candida CSF Culture

Frequently asked questions

What Does a Positive Result Mean?
A positive result indicates the presence of *Candida albicans* in your CSF, which could mean you have a fungal infection. Your doctor will work with you to determine the best treatment plan, which may include antifungal drugs.
What If My Results Are Negative?
A negative result means no *Candida albicans* was found in your CSF sample. However, other infections (bacterial, viral, or other fungal species) could still be causing your symptoms. Your doctor may recommend additional tests or repeat the culture if symptoms persist.
How Often Is This Test Repeated?
This test is typically done once, but your doctor may repeat it if symptoms worsen or if you’re at higher risk for infection (e.g., due to immune conditions or recent treatments). Follow-up may include other tests to rule out other causes of your symptoms.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy