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Candida albicans antibody, serum/plasma (immunoassay)

Published: August 9, 2026Updated: August 15, 2026

This blood test checks for antibodies to *Candida albicans*, a type of yeast that can cause infections. Antibodies are proteins your immune system makes in response to exposure to the yeast.

Quick summary

["Helps identify past or current immune response to *Candida albicans* in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
111309-1
Short code
CANDAB
Synonyms
C albicans Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube; red blood cells should be separated from serum within 2 hours of collection
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA) or Immunofluorescence Assay (IFA) for detection of Candida albicans-specific antibodies (IgG, IgM, IgA) in serum
CPT
86645
SNOMED
39512009
Specimen volume
1–2 mL serum (minimum 0.5 mL)
Stability
Stable at room temperature for 8 hours; refrigerated (2–8°C) for 7 days; frozen at -20°C or below for up to 6 months. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
500
Icterus max
20
TAT
24–72 hours
Order
routine

What Does This Test Measure?

The test detects antibodies produced by your immune system in response to *Candida albicans*, a fungus that can live in your body without causing illness in most people. These antibodies indicate your body has encountered the yeast, which may suggest past infection, chronic colonization, or immune response.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like persistent mouth, throat, or skin infections (e.g., thrush, vaginal yeast infections, or nail infections) that don’t improve with usual treatments. It may also be used in people with weakened immune systems (e.g., HIV, chemotherapy) or those with conditions like diabetes or HIV where yeast infections are more common.

When Might You Get False Results?

Results may not always match symptoms. A positive test could mean past exposure or immune activity, but it doesn’t always mean an active infection. A negative test doesn’t rule out infection—other tests or cultures may be needed.

What Does a Positive or Negative Result Mean?

A positive result suggests your immune system has detected *Candida albicans* antibodies, possibly from past exposure or chronic presence. A negative result means your body hasn’t produced these antibodies at detectable levels, but this doesn’t confirm no infection exists.

Reference range

Negative: <1:160 (IgG); Equivocal: 1:160–1:320; Positive: >1:320. Reference values vary by laboratory and assay method; results should be interpreted in conjunction with clinical findings.N/A

Specimen: serum

No fasting required. Patients on antifungal therapy should be noted as treatment may affect antibody titers. Avoid testing during active immunosuppressive therapy as results may be falsely negative.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis and Monitoring

Short name

Candida antibody test

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition. If you have recurring infections or a weakened immune system, your doctor may recommend retesting periodically to monitor changes in your immune response.
Can this test replace other diagnostic tests?
No. Antibody tests are screening tools. They’re often used alongside cultures (e.g., swabs) or other tests (like fungal blood cultures) to confirm or rule out active infections.
What if my test results are abnormal?
If your results are abnormal, discuss them with your doctor. They may recommend further testing, treatments, or adjustments to your care plan based on your symptoms and overall health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy