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Candida albicans antigen in serum/plasma (qualitative immunoassay)

Published: August 9, 2026Updated: August 15, 2026

This test checks for the presence of *Candida albicans*, a type of yeast that can cause infections, in your blood. It helps determine if you have a systemic fungal infection.

Quick summary

["This test helps doctors identify if *Candida* yeast has spread beyond the mouth or skin into your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
22163-0
Short code
CANDAB
Synonyms
C albicans Ab Ser-aCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top clot tube
Units
N/A
Ref low
80
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA) / Immunofluorescence Assay (IFA)
CPT
86628
SNOMED
43817-4
Specimen volume
1-2 mL serum (minimum 0.5 mL)
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
200
Icterus max
50
TAT
24–72 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like fever, chills, or unusual fatigue, especially after a recent medical procedure (such as surgery or a catheter insertion) that could allow yeast to enter your blood. It’s also used in people with weakened immune systems, like those with HIV/AIDS, cancer, or taking long-term steroids.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The test is usually done in a lab, and results are typically available within a few days.

What the Results Mean

A positive result means *Candida albicans* was detected in your blood, which could indicate a serious infection. A negative result means no detectable yeast was found, but other causes of symptoms may still need investigation.

Common Causes of False Results

False negatives can occur if the infection is mild or not actively spreading. False positives are rare but may happen if you have recent exposure to *Candida* (e.g., dental work) or certain medications.

Reference range

Negative: <1:80 titer or <10 U/mL; Equivocal: 1:80-1:160; Positive: >1:160 titer or >20 U/mL. Reference ranges vary by laboratory and assay methodology.N/A

Specimen: serum

No special preparation required. Fasting is not necessary.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Candida antigen blood test

Frequently asked questions

What does a positive result mean for my health?
A positive result suggests you may have a *Candida* bloodstream infection, which requires immediate medical attention. Your doctor will likely prescribe antifungal medications to treat it. Further testing may be needed to confirm the diagnosis and guide treatment.
Can this test detect all types of yeast infections?
This test specifically looks for *Candida albicans*, the most common type of yeast that causes blood infections. Other types of yeast (like *Candida krusei*) may not be detected by this test alone. Your doctor may recommend additional tests if needed.
How often should I get this test?
Only your doctor will determine if and when you need this test. It’s typically done as part of a diagnostic evaluation for suspected bloodstream infections, especially in high-risk patients.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy