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Candida albicans in Serum Culture (Qualitative)

Published: August 9, 2026Updated: August 15, 2026

This test checks for the presence of *Candida albicans*, a type of yeast, in your blood serum using a culture method. It helps identify infections caused by this fungus.

Quick summary

["A positive result may indicate a fungal bloodstream infection requiring medical evaluation and treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
33406-0
Short code
CANDCF
Synonyms
C albicans Ab Ser CF-aCnc
Category
chemistry
Sample
serum
Container
Red-top serum tube or serum separator tube (SST)
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
comp-fix
CPT
86171
SNOMED
74441003
Specimen volume
1-2 mL of serum
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
50
Icterus max
20
TAT
48–96 hours
Order
routine

What This Test Measures

The test involves collecting a blood sample from a vein and processing it to grow *Candida albicans* in a controlled environment. If the yeast is present, it will grow and be detected after several days. This method is qualitative, meaning it only tells you whether the yeast is present or not, not how much.

Why It’s Done

Your healthcare provider may order this test if you have symptoms of a fungal infection, such as fever, chills, or signs of infection in other parts of your body. It’s also used in patients with weakened immune systems (e.g., due to chemotherapy, HIV, or organ transplants) who are at higher risk for fungal infections.

How It’s Performed

A blood sample is drawn from a vein, typically in your arm. The sample is then sent to a lab where it is cultured to detect the presence of *Candida albicans* over time. Results are reported as either positive (yeast detected) or negative (no yeast detected).

What the Results Mean

A positive result means *Candida albicans* was found in your blood serum, suggesting a fungal infection. This requires further medical evaluation, including possible additional tests or treatment with antifungal medications. A negative result means no yeast was detected in this sample.

Reference range

Negative: <1:10 titer; Positive: ≥1:10 titer suggests exposure or active infection with Candida albicansN/A

Specimen: serum

No fasting required. Patient should be informed about the test purpose; avoid hemolyzed or lipemic samples. Inform clinician of any recent antifungal therapy as it may affect antibody levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing invasive fungal infections, particularly in high-risk patients. Early detection allows for prompt treatment to prevent complications such as organ damage or sepsis. However, false negatives can occur, so follow-up testing may be needed if symptoms persist.

Short name

Candida Culture (Serum)

Frequently asked questions

When might I get this test?
You may receive this test if you have symptoms like fever, fatigue, or unexplained infections, especially if you have a weakened immune system or recent medical procedures.
What does a positive result mean?
A positive result means *Candida albicans* was found in your blood, indicating a possible fungal bloodstream infection. Your doctor will work with you to determine the best course of treatment, which may include antifungal medications.
Can false results occur?
Yes, false negatives are possible, especially if the infection is mild or the sample was not taken at the right time. False positives are rare but can happen if other microbes are present. Your doctor will interpret results in the context of your symptoms and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy