Candida albicans antigen in serum/plasma (immunoassay)

What This Test Measures

The test looks for specific antigens produced by *Candida albicans*—a common yeast that can become harmful if it spreads beyond the mouth or skin into deeper tissues or the bloodstream. These antigens are released when the yeast invades body tissues, signaling an active infection.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fever, fatigue, or organ dysfunction (such as kidney or liver issues) combined with risk factors like weakened immunity (e.g., from HIV, chemotherapy, or long-term steroid use) or recent medical procedures (e.g., central venous catheters). It’s also used in patients with persistent fungal infections that don’t respond to initial treatments.

Common Uses in Clinical Practice

This test is particularly useful for monitoring patients with known or suspected invasive candidiasis (a severe infection affecting organs like the lungs, heart, or brain). It can help confirm diagnosis earlier than culture methods alone, especially in critically ill patients.

Sample Collection and Preparation

A blood sample is drawn from a vein in your arm. The blood is processed to separate serum or plasma (the liquid part of blood) for testing. The test uses an immunoassay to detect the yeast’s antigens with high sensitivity, often within 24 hours of collection.