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Candida albicans DNA in Serum/Plasma by Probe-Based Nucleotide Amplification Test

Published: August 9, 2026Updated: August 15, 2026

This test detects genetic material from *Candida albicans*, a type of yeast that can sometimes cause infections. It helps identify if this yeast is present in your blood or plasma.

Quick summary

["This test may help diagnose bloodstream infections caused by *Candida albicans* when other tests are inconclusive."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
90806-1
Short code
CALB-DNA
Synonyms
C albicans DNA Ser Ql NAA+probe
Category
chemistry
Sample
serum
Container
Sterile serum separator tube (SST) or red-top tube; transfer serum to a sterile, DNA-free cryovial for molecular testing
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
87481
SNOMED
122501007
Specimen volume
1-2 mL of serum
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or lower): 30 days; avoid repeated freeze-thaw cycles
Hemolysis max
2
Lipemia max
2
Icterus max
2
TAT
24–72 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fever, chills, or signs of infection (such as low blood pressure) and have been diagnosed with a fungal infection or weakened immune system. It may also be used if you have a history of invasive procedures that could introduce yeast into your bloodstream.

What to Expect Before the Test

No special preparation is typically needed. Your blood will be drawn from a vein, similar to other blood tests. You may feel a slight pinch, but it usually doesn’t cause significant discomfort.

What the Test Results Mean

The test looks for genetic material from *Candida albicans* in your blood or plasma. A positive result means the yeast’s DNA was found, which may indicate an infection. A negative result means no detectable DNA was found, but this doesn’t always rule out infection completely.

Possible Limitations

This test is highly sensitive for detecting *Candida albicans* DNA but may not catch all infections. False negatives can occur if the yeast isn’t actively multiplying in your blood at the time of testing. It’s often used alongside other diagnostic tools, such as blood cultures or clinical symptoms.

Reference range

Negative (Candida albicans DNA not detected)N/A

Specimen: serum

No special patient preparation is required. Specimen should be collected prior to initiation of antifungal therapy when possible, as antifungal treatment may reduce pathogen DNA load and affect test sensitivity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Candida DNA Test (Serum/Plasma)

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of *Candida albicans* genetic material in your blood or plasma, which may indicate an infection. Your healthcare provider will discuss next steps, such as further testing or treatment options.
Can this test replace a blood culture?
No, this test is not a replacement for blood cultures. Blood cultures are the gold standard for diagnosing infections, as they directly grow the yeast in a lab. This test complements blood cultures by detecting genetic material, which can help confirm infection faster.
How soon will I get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will contact you to discuss the findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy