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Candida albicans detection by quantitative polymerase chain reaction (PCR) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of *Candida albicans*, a type of yeast that can cause infections, by analyzing a small sample of your blood.

Quick summary

["It helps diagnose invasive fungal infections when other tests are inconclusive."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105886-6
Short code
CANDPCR
Synonyms
C albicans DNA Vag Ql
Category
chemistry
Sample
serum
Container
Sterile container or nucleic acid transport medium (e.g., Aptima vaginal swab transport tube, Copan ESwab, or similar molecular transport device)
Units
N/A
Fasting
false
Population
adult
Sex
female
Age range
12–99 years
Method
Nucleic acid amplification test (NAAT), typically real-time polymerase chain reaction (PCR)
CPT
87798 (infectious agent detection by nucleic acid, not otherwise specified) or 87481 (Candida species, amplified probe technique)
SNOMED
122450008 | Candida albicans investigation (procedure) or 609328004 | Detection of Candida albicans (procedure)
Specimen volume
1 vaginal swab (flocked or polyester swab)
Stability
Room temperature: 24-48 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days (varies by transport medium manufacturer)
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What Is This Test Measuring?

The test detects genetic material (DNA) from *Candida albicans* using PCR, a highly sensitive method that amplifies tiny amounts of DNA for detection. This is different from traditional blood cultures, which focus on growing the organism in a lab.

Why Might You Need This Test?

You may receive this test if you have symptoms of a fungal infection (e.g., fever, persistent mouth/throat sores) or risk factors like weakened immunity, recent surgery, or prolonged use of broad-spectrum antibiotics.

When Might Results Be Abnormal?

Positive results suggest *Candida albicans* is present in your blood, which could indicate invasive candidiasis (a serious infection). Negative results mean no detectable DNA from this yeast, but other causes of symptoms may still exist.

What Does This Test Tell You About My Health?

While this test confirms the presence of *Candida albicans*, it does not measure infection severity or guide treatment directly. Results are used alongside clinical findings (e.g., symptoms, lab markers) to guide decisions with your healthcare provider.

Reference range

Negative (no Candida albicans DNA detected). Positive results indicate presence of Candida albicans DNA.N/A

Specimen: serum

Patient should avoid douching, vaginal creams, suppositories, or sexual intercourse for 24-48 hours prior to specimen collection. Specimen should be collected prior to initiation of antifungal therapy when possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis and Monitoring

Short name

Candida PCR (Serum/Plasma)

Frequently asked questions

How often will I need this test?
Results depend on your symptoms and risk factors. Your doctor may order it once or repeatedly if you’re at high risk for invasive fungal infections.
What if my results are positive?
A positive result means *Candida albicans* DNA was found in your blood, prompting further evaluation (e.g., imaging, cultures) to confirm infection. Treatment may include antifungal medications tailored to your condition.
Can I take anything to prepare for this test?
No special preparation is needed. Blood is drawn like a standard blood test, and fasting is not required.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy