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Candida albicans IgG Antibody (Serum or Plasma)

Published: August 9, 2026Updated: August 15, 2026

This test measures the level of antibodies your immune system produces in response to a yeast called *Candida albicans*, which can sometimes cause infections.

Quick summary

["Helps assess immune response to *Candida* yeast, potentially identifying past exposure or mild systemic infection risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
56204-1
Short code
CALBG4
Synonyms
C albicans IgG4-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant
Units
N/A
Ref low
5
Ref high
10
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA)
CPT
86645
SNOMED
122386001
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What This Test Measures

IgG antibodies are part of your immune system’s long-term defense. If your body has encountered *Candida albicans* before, your immune system may produce these antibodies. This test checks for their presence in your blood, though it doesn’t always indicate an active infection.

Why It Might Be Ordered

Doctors may order this test if you have symptoms like persistent mouth or throat thrush, recurrent fungal infections, or if you’re immunocompromised (e.g., due to HIV, chemotherapy, or long-term steroids). It can also help monitor immune response in certain conditions.

Specimen and Preparation

A blood sample is drawn from a vein in your arm. No special preparation is needed, but fasting may not be required unless your doctor specifies. The sample is tested for IgG antibodies using an immunoassay method.

What the Results Mean

A positive result means your body has likely encountered *Candida albicans* at some point, but it doesn’t confirm an active infection. High levels may suggest past exposure or a weakened immune response. Always discuss results with your healthcare provider.

Reference range

Negative: <5 AU/mL; Equivocal: 5-10 AU/mL; Positive: >10 AU/mL (reference values may vary by laboratory)N/A

Specimen: serum

No special preparation required. Specimen should be collected before initiation of antifungal therapy when possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to Candida albicans

Frequently asked questions

What does a positive result mean?
A positive result suggests your immune system has recognized *Candida albicans* before, but it doesn’t prove you have an active infection. It may indicate past exposure or a mild immune response. Your doctor will consider other factors, like symptoms and test results, to determine next steps.
Can this test detect an active Candida infection?
No, this test does not directly detect an active infection. It measures antibodies, which reflect past exposure or immune activity. For diagnosing an active *Candida* infection, doctors may use cultures, symptoms, or other tests.
Is fasting required for this test?
No fasting is typically required for this blood test. However, always follow your doctor’s instructions for any specific preparations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy