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Calcitonin, Serum/Plasma — 10 Minutes After IV Calcium, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures calcitonin 10 minutes after IV calcium is given during a calcium stimulation test to help evaluate thyroid C-cell function.

Quick summary

["This timed calcitonin measurement is usually interpreted with the baseline result and other thyroid tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50180-9
Short code
Calcit 10M p CPG IV SerPl-mCnc
Synonyms
Calcit 10M p CPG IV SerPl-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the concentration of calcitonin in serum or plasma 10 minutes after calcium is given intravenously. It is part of a calcium stimulation test used to evaluate how the thyroid's C cells respond.

Why might I need this test?

Calcitonin testing may be used when there is concern for medullary thyroid carcinoma or C-cell hyperplasia, particularly with an abnormal baseline result, a suspicious thyroid finding, or a relevant family history. The stimulated measurement can provide additional information about C-cell activity.

How is the test performed?

A baseline blood sample is collected before a controlled dose of calcium is given intravenously. A second sample is then collected at the specified time, such as 10 minutes afterward, and both calcitonin measurements are interpreted together.

How do I prepare for the test?

Follow the testing center's instructions because this test requires precisely timed blood collection. Do not stop prescribed medicines unless your clinician advises you to, and tell the care team if you have kidney disease, low blood calcium, or a history of reactions to IV calcium.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated baseline or stimulated calcitonin level can indicate increased thyroid C-cell activity and may raise concern for medullary thyroid carcinoma or C-cell hyperplasia. A rise after calcium stimulation may be clinically meaningful even when the baseline result is not clearly elevated. Results should be interpreted by a clinician alongside thyroid imaging, family history, genetic testing when appropriate, and other laboratory findings.

Short name

10-minute post-calcium calcitonin

Frequently asked questions

Why is a baseline calcitonin test needed?
The 10-minute result is usually compared with the level collected before IV calcium. This shows how much the thyroid C cells increase calcitonin release in response to stimulation.
Does an abnormal result mean I have cancer?
No. An abnormal calcitonin result does not by itself diagnose cancer. Other causes of increased C-cell activity and the results of additional evaluation must be considered.
Is fasting required for this test?
Fasting requirements depend on the laboratory and the calcium stimulation protocol. Follow the specific instructions provided by the testing center, especially because the blood samples must be collected at exact times.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy