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Calcium, Serum or Plasma, Substance Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium in your blood, which is important for many body functions, including muscle and nerve activity.

Quick summary

["Calcium helps your body stay strong and supports normal heart rhythm and blood clotting."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
77667-4
Short code
CALCT-2PC
Synonyms
Calcit 2M p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST, tiger-top) or plain red-top tube for serum; lithium heparin or EDTA plasma tubes are acceptable alternatives.
Units
N/A
Ref low
0
Ref high
11.8
Fasting
false
Population
adult
Sex
all
Age range
18–99 years
Method
Chemiluminescent Immunoassay (CLIA) or Electrochemiluminescence Immunoassay (ECLIA)
CPT
82308
SNOMED
39503006
Specimen volume
1-2 mL of serum or plasma (minimum 0.5 mL)
Stability
Serum/plasma stable for 8 hours at room temperature; 24 hours refrigerated at 2-8°C; for longer storage, freeze at -20°C or below for up to 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
50
Lipemia max
100
Icterus max
25
TAT
24–72 hours
Order
routine

Why It’s Done

Your doctor may order this test to check for conditions like low or high calcium levels, which can affect bones, muscles, nerves, or heart. It’s also used to diagnose or monitor conditions such as kidney disease, vitamin D deficiency, or certain cancers.

What to Expect

A blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it shouldn’t cause discomfort. The test is quick and doesn’t require special preparation.

Normal vs. Abnormal Results

Results don’t include specific reference ranges. Your doctor will compare your result to your individual health needs and any known conditions.

Common Conditions Affecting Results

Low calcium (hypocalcemia) may cause muscle spasms, numbness, or irregular heartbeat. High calcium (hypercalcemia) could lead to fatigue, nausea, or kidney problems. Both can be linked to underlying health issues.

Reference range

Reference values vary by laboratory; basal calcitonin in adult males typically <11.8 pg/mL and in adult females typically <4.8 pg/mL. Post-stimulation calcitonin values depend on the provocative agent (e.g., calcium or pentagastrin) and clinical context. A peak post-stimulation calcitonin >100 pg/mL is highly suggestive of medullary thyroid carcinoma (MTC).N/A

Specimen: serum

Fasting is not required. However, patients should be informed that the test involves a specific provocative stimulation protocol (calcium or pentagastrin infusion). No special dietary restrictions are generally needed prior to the baseline draw, but caffeine intake should be avoided prior to testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal calcium levels can signal serious health issues, such as metabolic bone disease, thyroid disorders, or kidney problems. Regular monitoring helps manage these conditions and prevent complications.

Short name

Calcium Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 24 to 48 hours, depending on your lab’s processing time. Your doctor will contact you with the final report.
What should I do if my calcium level is out of range?
If your results are abnormal, your doctor will discuss next steps, which may include further testing, lifestyle changes, or treatment to balance your calcium levels.
Can diet affect calcium test results?
Yes, eating foods high in calcium (like dairy, leafy greens) or supplements can temporarily affect results. Your doctor may advise fasting or timing your test to avoid interference.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy