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Calcium, Serum or Plasma, Mass Concentration

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of calcium in your blood, which is important for many body functions, including muscle and nerve activity.

Quick summary

["Your calcium levels help ensure strong bones, proper muscle function, and healthy nerve signals."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
16506-8
Short code
CALC3HR
Synonyms
Calcit 3h p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top serum tube or serum separator tube (SST)
Units
N/A
Ref low
0
Ref high
10
Critical range
20 N/A – 400 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Chemiluminescent or Radioimmunoassay)
CPT
82308
SNOMED
395940009
Specimen volume
1 mL serum
Stability
Serum is stable for 8 hours at room temperature, 24 hours at 2-8°C, and up to 30 days at -20°C or colder. For prolonged storage, freeze at -70°C.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Doctors may order a calcium test to check for conditions like low or high calcium levels, which can affect bones, muscles, or heart function. It might also be done if you have symptoms such as muscle spasms, confusion, or unusual fatigue.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves a blood draw, but this depends on your doctor’s instructions. Bring any medications you’re currently taking.

How the Test Is Done

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it’s usually over quickly. The blood sample is sent to a lab for analysis.

What the Results Mean

Results are reported in milligrams per deciliter (mg/dL). Low calcium can cause weakness or numbness, while high levels may lead to kidney stones or irregular heart rhythms. Your doctor will interpret results based on your overall health.

Reference range

Reference values vary by stimulation test and laboratory method. Generally, basal calcitonin in adults is <10 pg/mL (males) and <5 pg/mL (females). Post-challenge peak values depend on the provocative agent used; typically a rise >100 pg/mL in males or >50 pg/mL in females is suggestive of medullary thyroid carcinoma.N/A

Specimen: serum

No special patient preparation is typically required. Patient should remain supine for at least 15 minutes prior to and during specimen collection. Information regarding the specific provocative agent administered (e.g., calcium, pentagastrin) should be documented with the specimen.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal calcium levels can signal underlying issues like kidney disease, thyroid disorders, or conditions affecting bone metabolism. Chronic imbalances may require treatment to prevent long-term damage to organs or nerves.

Short name

Calcium Level

Frequently asked questions

What causes low calcium levels?
Low calcium can result from dietary deficiencies, certain medications (like antacids), or conditions like vitamin D deficiency, kidney problems, or chronic pancreatitis.
What causes high calcium levels?
High calcium is often linked to overactive thyroid (hyperparathyroidism), kidney disease, or prolonged use of certain medications. Rarely, it can be caused by tumors or excessive vitamin D intake.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow up with your doctor if you have questions about your results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy