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Calcium in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium present in your blood serum, an important mineral that helps maintain strong bones, healthy nerves, and proper muscle function.

Quick summary

["Your blood calcium levels help your body stay strong and function normally."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
58892-1
Short code
CALB
Synonyms
Calcit BS SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube; plasma may be collected in EDTA or heparin tubes
Units
N/A
Ref low
0
Ref high
11.5
Critical range
— – 100 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Chemiluminescent or ELISA)
CPT
82308
SNOMED
1002541000009103
Specimen volume
1.0 mL serum or plasma
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 24 hours; Frozen (-20°C or lower): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
500
Icterus max
25
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Doctors may order a serum calcium test to check for conditions like low or high calcium levels, which can cause symptoms such as muscle cramps, bone pain, or irregular heartbeat. It’s also used to diagnose or monitor diseases like kidney problems, osteoporosis, or certain cancers.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel. Bring any medications you’re taking to your doctor’s office.

During the Test

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample is then sent to a lab for analysis.

Possible Results and Next Steps

Results are typically reported in milligrams per deciliter (mg/dL). If your levels are outside the normal range, your doctor may recommend further testing or treatments, such as dietary changes, supplements, or medications.

Reference range

Males: <11.5 pg/mL; Females: <4.6 pg/mL (values may vary by assay method and laboratory)N/A

Specimen: serum

No special preparation required. For stimulation testing, refer to calcium or pentagastrin stimulation protocols. Patient should be informed about the purpose of baseline testing prior to possible thyroid surgery or evaluation of thyroid nodules.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Calcium

Frequently asked questions

What Does an Abnormal Result Mean?
Low calcium levels (hypocalcemia) can lead to muscle spasms, numbness, or an increased risk of bone fractures. High calcium levels (hypercalcemia) may cause fatigue, nausea, or kidney stones. Your doctor will interpret results in the context of your overall health and may order additional tests if needed.
How Often Should I Get This Test?
This test is often done as part of a routine checkup or when symptoms suggest calcium-related issues. Your doctor will determine how frequently you need it based on your health status and medical history.
Can I Avoid This Test?
No, this test is essential for monitoring calcium balance, especially if you have conditions like kidney disease, thyroid disorders, or osteoporosis. Skipping it may delay diagnosis and treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy