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Calcitonin Precursor Protein (Calcitonin), Serum/Plasma — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures calcitonin in blood. The test is mainly used to evaluate thyroid abnormalities and may help assess possible medullary thyroid cancer.

Quick summary

["An elevated calcitonin level may suggest a thyroid or other neuroendocrine condition, but other causes must also be considered."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50184-1
Short code
Calcit pre CPG IV SerPl-mCnc
Synonyms
Calcit pre CPG IV SerPl-mCnc
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This blood test measures the amount of calcitonin, a protein made mainly by specialized thyroid cells called C cells. Calcitonin is released into the bloodstream and can be measured in serum or plasma.

Why might I need this test?

Calcitonin may be ordered when thyroid nodules or other findings raise concern for medullary thyroid carcinoma, a rare type of thyroid cancer. It may also be used to help evaluate certain other neuroendocrine conditions or to monitor a patient being evaluated for one of these conditions.

How is the test performed?

A blood sample is collected by venipuncture. The laboratory separates serum or plasma from the blood and measures the calcitonin concentration using a laboratory assay.

How do I prepare for the test?

Fasting is usually not required, but follow any instructions provided by your healthcare professional or the laboratory. Tell the care team about medications and supplements because some can affect test results or interfere with laboratory assays.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Calcitonin, Serum/Plasma

Frequently asked questions

Does an elevated calcitonin level mean I have cancer?
No. Elevated calcitonin has several possible causes, including thyroid disorders, other neuroendocrine conditions, kidney problems, and medication effects. Additional testing may be needed to determine the cause.
Do I need to fast before this blood test?
Fasting is usually not necessary. Follow the preparation instructions provided by your healthcare professional or laboratory, especially if you are taking medications or supplements.
Can medications or supplements affect the result?
Yes. Some medications and supplements can alter calcitonin levels or interfere with the laboratory assay. Inform your care team about everything you take so the result can be interpreted appropriately.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy