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Calcium, Serum or Plasma, Mass Concentration

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium in your blood, which is important for many body functions, including muscle and nerve activity, bone health, and blood clotting.

Quick summary

["Your calcium levels help ensure strong bones, proper muscle function, and healthy blood clotting."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
51430-7
Short code
CT-PREPOST
Synonyms
Calcit pre/p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube; Plasma may use EDTA or heparin tubes per laboratory protocol
Units
N/A
Ref low
0
Ref high
10
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Chemiluminescent or Radioimmunoassay)
CPT
82308
SNOMED
39521008
Specimen volume
1.0-2.0 mL of serum or plasma; minimum 0.5 mL
Stability
Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days; Avoid repeated freeze-thaw cycles
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–96 hours
Order
routine

Why Is This Test Done?

Doctors may order a calcium test to check for conditions like low or high calcium levels (hypocalcemia or hypercalcemia), bone diseases, kidney problems, or metabolic disorders. It can also be part of routine health checks or when symptoms like muscle cramps, fatigue, or frequent fractures appear.

What to Expect During the Test

A small blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and doesn’t require special preparation. The sample is sent to a lab for analysis.

Possible Causes of Abnormal Results

Low calcium levels might be due to conditions like vitamin D deficiency, kidney disease, or certain medications. High levels could result from overactive thyroid, cancer, or prolonged immobilization. Your doctor will discuss these with you based on your symptoms and other test results.

What You Should Know Before Testing

No special preparation is needed, but inform your doctor about any medications (like calcium supplements or certain blood pressure drugs) or health conditions you have. Avoid drinking large amounts of calcium-rich foods or supplements right before testing if instructed.

Reference range

Basal: <10 pg/mL (male), <5 pg/mL (female); Pentagastrin-stimulated peak varies by clinical context; Calcium-stimulated peak: <100 pg/mL (males), <70 pg/mL (females)N/A

Specimen: serum

No special preparation required for basal sample. For stimulation testing, patient should fast overnight (8-12 hours). Discontinue calcium supplements 24 hours prior if calcium stimulation is used. Avoid biotin supplements for at least 72 hours before testing as biotin may interfere with immunoassays.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Calcium Level

Frequently asked questions

How does calcium affect my overall health?
Calcium is vital for many bodily functions. Low levels can cause muscle spasms, weakness, or even seizures, while high levels may lead to nausea, confusion, or kidney stones. Your doctor will review your results alongside other symptoms and tests to determine if treatment is needed.
What if my calcium level is out of range?
If your calcium level is abnormal, your doctor may recommend further tests or treatments, such as adjusting medications, improving vitamin D intake, or managing underlying conditions like kidney disease. Follow-up visits will help monitor changes over time.
Can diet affect calcium test results?
Yes, diet can influence calcium levels. High calcium intake from foods or supplements right before testing might temporarily raise your result. Avoid large amounts of dairy, leafy greens, or calcium-fortified drinks unless advised otherwise by your doctor.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy