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Calcium in Serum or Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of calcium, a mineral essential for many body functions, including muscle and nerve activity, blood clotting, and bone health.

Quick summary

["Your calcium level helps doctors assess bone health, muscle function, and overall mineral balance in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1992-7
Short code
CALC
Synonyms
Calcit SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube; plasma acceptable in EDTA or heparin tubes
Units
N/A
Ref low
0
Ref high
8
Critical range
— – 100 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Chemiluminescent)
CPT
82308
SNOMED
1005733001
Specimen volume
1.0 mL (minimum 0.5 mL)
Stability
Room temperature: 4 hours; Refrigerated (2-8°C): 24 hours; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Doctors may order a calcium test to check for conditions like low or high calcium levels, which can cause symptoms such as muscle cramps, weakness, or abnormal heart rhythms. It’s also used to monitor conditions like osteoporosis, kidney disease, or hyperparathyroidism.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood. If you’re on certain medications (like calcium supplements or diuretics), let your healthcare provider know.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab for analysis using an automated method to measure calcium levels accurately.

What Are the Results Mean?

Results are compared to standard reference ranges, but your doctor will interpret them based on your overall health and symptoms. Very high or low levels may trigger further testing or treatment.

Reference range

Male: <8.0 pg/mL; Female: <5.0 pg/mL (values vary by assay method and laboratory)N/A

Specimen: serum

No fasting required. Patient should be well-hydrated. Recent administration of radioisotopes may interfere with some assay methods.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal calcium levels can indicate underlying health issues, such as bone disorders, kidney problems, or hormonal imbalances. Low calcium (hypocalcemia) may lead to muscle spasms or fatigue, while high calcium (hypercalcemia) could cause nausea, confusion, or kidney stones. Regular monitoring helps manage these conditions effectively.

Short name

Calcium Level

Frequently asked questions

What causes abnormal calcium levels?
Abnormal calcium levels can result from dietary imbalances, kidney or thyroid disorders, certain medications, or conditions like osteoporosis. Symptoms may include fatigue, muscle weakness, or bone pain.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready for review.
Can I eat or drink before the test?
If fasting is required (e.g., for blood tests), avoid food and liquids (except water) for 8–12 hours beforehand. If no fasting is needed, you can eat and drink normally.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy