Skip to content

Calcium, Serum or Plasma Concentration

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium in your blood, which is important for keeping bones strong, muscles working properly, and nerves functioning correctly.

Quick summary

["Your calcium level helps ensure healthy bones, muscle function, and nerve signaling."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
15035-9
Short code
CALC
Synonyms
Calcit SerPl-sCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant for serum; EDTA or heparinized plasma tube for plasma specimens
Units
N/A
Ref low
0
Ref high
11.5
Critical range
— – 100 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Immunoassay (Chemiluminescent Immunoassay [CLIA] or Radioimmunoassay [RIA])
CPT
82308
SNOMED
39579003
Specimen volume
1.0 mL serum or plasma (minimum 0.5 mL)
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 24 hours; Frozen (-20°C or lower): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
300
Icterus max
40
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Doctors may order a calcium test to check for conditions like low or high calcium levels, which can cause symptoms such as muscle cramps, weakness, or irregular heartbeats. It may also be used to monitor bone health, kidney function, or response to treatments like calcium supplements or medications.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves a blood draw, but this depends on your doctor’s instructions. Bring any medications you’re taking to your appointment.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. The sample is then sent to a lab for analysis to measure calcium concentration in your serum or plasma.

What Are Possible Results?

Results are reported as a numerical value representing calcium concentration in milligrams per deciliter (mg/dL). Your doctor will interpret the result in relation to your health and symptoms.

Reference range

Reference ranges vary by assay method and laboratory. Typical adult reference ranges: Male: <11.5 pg/mL (<3.4 pmol/L); Female: <4.6 pg/mL (<1.4 pmol/L). Pediatric and neonatal ranges differ significantly.N/A

Specimen: serum

No fasting required. Patient should be well-hydrated. Avoid recent radioisotope administration. Pentagastrin stimulation testing may be performed for patients with borderline elevated basal calcitonin levels or for screening of family members with MEN2 syndromes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low calcium (hypocalcemia) can lead to muscle spasms, numbness, or irregular heart rhythms, while high calcium (hypercalcemia) may cause fatigue, nausea, or kidney stones. These imbalances can stem from conditions like vitamin D deficiency, kidney disease, or certain cancers.

Short name

Calcium Level

Frequently asked questions

What causes my calcium level to be checked?
Your doctor may recommend this test if you have symptoms like muscle weakness, bone pain, or frequent fractures, or if you have conditions like osteoporosis, kidney disease, or thyroid disorders.
How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
Check with your doctor or lab for specific instructions, but fasting may be required for some blood tests. Generally, you can drink water unless advised otherwise.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy