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Calcium, Serum or Plasma, Mass Concentration

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium in your blood, which is important for many body functions, including muscle and nerve activity, bone health, and blood clotting.

Quick summary

["Your calcium levels help ensure your body stays balanced and functions properly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
12510-4
Short code
CALC6
Synonyms
Calcit sp6 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube (no anticoagulant). Plasma may be collected in EDTA or heparin tubes depending on assay requirements.
Units
N/A
Ref low
0
Ref high
11.5
Critical range
— – 1000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (Chemiluminescent or Radioimmunoassay)
CPT
82308
SNOMED
313803006
Specimen volume
1.0 mL serum or plasma (minimum 0.5 mL)
Stability
Serum/plasma stable for 8 hours at room temperature, 24 hours at 2-8°C, and up to 30 days at -20°C or colder. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
200
Icterus max
40
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Doctors may order a calcium test to check for conditions like low or high calcium levels, which can cause symptoms such as muscle cramps, weakness, or irregular heartbeats. It may also be done to monitor bone health, kidney function, or certain medical treatments.

What Does the Test Involve?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis. The test measures the calcium concentration in your blood plasma or serum.

What Are Common Causes of Abnormal Results?

Low calcium levels (hypocalcemia) can occur due to conditions like vitamin D deficiency, kidney problems, or certain medications. High calcium levels (hypercalcemia) may result from overactive thyroid, bone diseases, or prolonged immobilization.

How Is the Test Performed?

The test is typically performed using a blood draw, where a healthcare professional inserts a needle into your arm to collect blood. The sample is then analyzed in a lab using automated equipment to measure calcium concentration.

Reference range

Basal calcitonin: Male <11.5 pg/mL, Female <4.6 pg/mL. Pentagastrin-stimulated peak values vary; stimulated calcitonin levels above 100 pg/mL in males or 50 pg/mL in females are suggestive of medullary thyroid carcinoma (MTC). Interpretation of 6th specimen post-stimulation should be compared to baseline and established reference ranges for the specific challenge protocol used.N/A

Specimen: serum

No special fasting required. Patient should be informed about the provocative stimulation procedure (e.g., pentagastrin or calcium infusion challenge). The 6th specimen is collected at a defined time point post-challenge as part of a serial sampling protocol. Avoid recent radioisotope studies that may interfere with immunometric assays.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal calcium levels can affect many body systems. Low calcium can lead to muscle spasms, numbness, and increased risk of bone fractures. High calcium can cause fatigue, nausea, and kidney stones. Regular monitoring is important for patients with conditions like osteoporosis, kidney disease, or those on long-term calcium-regulating medications.

Short name

Calcium Level

Frequently asked questions

What are the normal ranges for calcium levels?
Normal calcium levels can vary slightly between labs, but generally, the reference range for serum or plasma calcium is between 8.4 and 10.2 milligrams per deciliter (mg/dL). Your specific range may differ based on your lab’s standards.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition, symptoms, and medical history. Some people may need it yearly, while others may need it more or less frequently.
Can diet affect calcium test results?
Yes, diet can influence calcium levels. Consuming too much calcium or certain foods and supplements can temporarily alter your test results. It’s best to avoid large calcium supplements or dairy products for 24 hours before the test if instructed by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy