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Calcium in Serum (Total)

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of calcium, a mineral essential for bone health, muscle function, and nerve signaling, in your blood serum.

Quick summary

["Your blood calcium levels help ensure proper bone strength and vital bodily processes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
16510-0
Short code
CALC8
Synonyms
Calcit sp8 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top serum tube or serum separator tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–99 years
Method
Immunoassay (Chemiluminescent or Radioimmunoassay)
CPT
82308
SNOMED
39520004
Specimen volume
1-2 mL of serum
Stability
Serum stable for 8 hours at room temperature, 24 hours at 2-8°C, and up to 3 months at -20°C or colder
Hemolysis max
100
Lipemia max
500
Icterus max
25
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions like low or high calcium levels, which can affect heart rhythm, muscle function, or bone health. It’s often done when symptoms such as muscle cramps, fatigue, or abnormal heartbeats are present.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic panel, but this depends on your doctor’s instructions.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL). While exact ranges vary by lab, low levels may indicate conditions like hypoparathyroidism, while high levels could suggest kidney disease or overuse of certain medications.

Common Conditions Linked to Abnormal Results

Low calcium levels (hypocalcemia) may cause muscle spasms, numbness, or irregular heartbeats. High calcium levels (hypercalcemia) can lead to fatigue, nausea, or kidney stones.

Reference range

Reference ranges for post-stimulation calcitonin vary by laboratory and assay methodology; results should be interpreted in conjunction with the stimulation test protocol and clinical context.N/A

Specimen: serum

No special preparation required. Patient should be informed about the stimulation challenge procedure (e.g., calcium or pentagastrin infusion) and the 8th specimen collection timing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Serum Calcium

Frequently asked questions

What causes my calcium test results to be different from what I’ve heard in the news or online?
Reference ranges can vary slightly between labs due to different testing methods or patient populations. Always rely on your doctor’s interpretation of your specific results.
Can I eat or drink anything before this test?
Check with your doctor or lab technician about fasting requirements. Some tests are done on an empty stomach, while others may not require fasting.
Will I feel any pain or discomfort during the blood draw?
Most people experience only mild discomfort or a slight pinch during the blood draw. Most people recover quickly afterward.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy