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Calciumrbcscnc

Published: July 31, 2026Updated: August 10, 2026

A blood test that measures the amount of calcium inside your red blood cells to help evaluate your body's calcium status.

Quick summary

{"Measures calcium levels inside red blood cells","Requires a simple blood sample","Helps diagnose conditions affecting calcium balance","May be used to monitor certain treatments"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
25583-6
Short code
RBC Ca
Synonyms
Calcium RBC-sCnc
Category
electrolyte
Sample
whole-blood
Container
Lavender top (K2-EDTA) tube or royal blue top (EDTA) trace metal-free collection tube
Units
not specified
Ref low
0.015
Ref high
0.025
Critical range
0.3 not specified – 1.5 not specified
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
CPT
82310
SNOMED
271583001
Specimen volume
2-3 mL whole blood
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Avoid freezing whole blood specimen
Hemolysis max
50
Lipemia max
300
Icterus max
20
TAT
24–72 hours
Order
routine

What is this test?

The Red Blood Cell Calcium test measures the amount of calcium present inside your red blood cells (erythrocytes). While most routine calcium tests measure calcium in the liquid part of your blood (serum), this test specifically looks at intracellular calcium—the calcium contained within the cells themselves. This can provide different and sometimes more accurate information about your body's calcium status, especially in certain medical conditions.

Why is it ordered?

Your healthcare provider may order this test to: evaluate calcium metabolism disorders, investigate conditions that affect cell membrane function, assess certain kidney diseases, monitor patients on long-term dialysis, or investigate unexplained fatigue, muscle weakness, or abnormal heart rhythms. It may also be useful in monitoring the effectiveness of calcium supplements or other treatments.

How is the test performed?

A healthcare professional will draw a small sample of blood from a vein in your arm using a needle. The sample is then processed in a laboratory to separate the red blood cells and measure the calcium content within them. The procedure is quick and similar to other routine blood tests.

How to prepare

Follow your healthcare provider's instructions regarding fasting or medication adjustments. Some medications may affect calcium levels, so inform your doctor about all medications and supplements you are taking. No special preparation is usually required beyond following your provider's specific instructions.

Reference range

0.015-0.025 mmol/Lnot specified

Specimen: whole-blood

No special preparation or fasting required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is this test different from a regular calcium blood test?
Yes. Regular calcium tests measure calcium in the liquid portion of your blood (serum calcium). This test measures calcium inside the red blood cells, which may provide different information about your calcium status and cellular health. Your doctor chooses the most appropriate test based on your specific medical situation.
Do I need to fast before this test?
Follow your healthcare provider's specific instructions. Fasting may or may not be required depending on your situation. Always confirm preparation instructions with your doctor or the testing laboratory.
What do abnormal results mean?
Abnormal results do not necessarily mean you have a serious condition. Many factors can affect RBC calcium levels. Your healthcare provider will interpret your results in context with your overall health, symptoms, and other test results. They will discuss any necessary follow-up steps with you.
Are there any risks from this test?
The risks are minimal and similar to routine blood tests, including slight bruising, bleeding, or rare infection at the puncture site. The procedure is generally well-tolerated.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy