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Candida Antigen Quantitative (Serum/Plasma)

Published: August 9, 2026Updated: August 15, 2026

This test measures the presence of fungal antigens from *Candida* species in your blood, helping detect infections caused by yeast like *Candida albicans*.

Quick summary

["Detects bloodstream *Candida* infections, which can be life-threatening if untreated."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
43067-8
Short code
CANDAB
Synonyms
Candida Ab Titr Ser
Category
chemistry
Sample
serum
Container
Serum Separator Tube (SST) or Red Top Tube
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA) / Immunofluorescence Assay (IFA)
CPT
86644
SNOMED
122375008
Specimen volume
1-2 mL serum (minimum 0.5 mL)
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
200
Icterus max
50
TAT
24–96 hours
Order
routine

What Does This Test Measure?

The test identifies specific antigens produced by *Candida* yeast, which may indicate an active infection. These antigens are not always present in healthy individuals, so a positive result suggests infection but does not confirm the exact type of *Candida* species or severity. Blood cultures or other tests may be needed for further evaluation.

When Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like fever, chills, or signs of infection (e.g., in the blood, lungs, or other organs). It’s also used in patients with weakened immune systems (e.g., due to HIV, chemotherapy, or organ transplants) or those with long-term medical devices (like catheters).

How Is the Test Performed?

A blood sample is drawn from a vein, typically in your arm. The sample is then analyzed in a lab to detect *Candida* antigens using a sensitive immunoassay method. Results are usually available within 24–48 hours.

What Are Possible Results?

A **negative** result means no detectable *Candida* antigens were found in your blood sample. A **positive** result suggests possible infection but does not confirm the diagnosis alone. Follow-up tests (like blood cultures) may be needed to confirm or investigate further.

Reference range

Titer <1:80 or negative; results reported as serial dilutions (e.g., 1:40, 1:80, 1:160, 1:320, 1:640). Titers ≥1:160 may suggest active or recent infection.N/A

Specimen: serum

No fasting required. Specimen should be collected prior to initiation of antifungal therapy when possible, as treatment may affect antibody titers.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Candida Blood Test

Frequently asked questions

Why was this test ordered?
Your provider may have suspected *Candida* infection based on symptoms, risk factors (e.g., IV catheters, immune suppression), or lab findings (e.g., elevated white blood cells). This test helps confirm or rule out bloodstream infection, guiding treatment decisions.
What does a positive result mean?
A positive result strongly suggests *Candida* bloodstream infection, which requires immediate medical attention. Treatment typically involves antifungal medications tailored to your specific needs. A negative result means no detectable antigens, but other tests may still be needed to diagnose infection elsewhere.
Could this test cause side effects?
No, the blood draw itself is the only procedure-related discomfort, which is mild (e.g., bruising or slight pain at the site). The test itself does not cause side effects. If you have questions about the procedure, ask your provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy