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Candida Antigen in Serum (Quantitative)

Published: August 9, 2026Updated: August 15, 2026

This test measures the presence of fungal antigens from *Candida* species in your blood serum, helping detect fungal infections like candidiasis.

Quick summary

["This test helps diagnose serious fungal infections that may require treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
35271-6
Short code
CANDAG
Synonyms
Candida Ag Ser Ql LA
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Latex agglutination
CPT
87449
SNOMED
122706005
Specimen volume
1-2 mL serum
Stability
Stable for 7 days at 2-8°C; store at -20°C for longer storage
Hemolysis max
200
Lipemia max
100
Icterus max
50
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific antigens produced by *Candida* yeasts in your blood. These antigens are not present in healthy individuals but can appear if *Candida* has spread beyond the mouth, skin, or gut into the bloodstream, causing a systemic infection.

When You Might Need This Test

Your healthcare provider may order this test if you have symptoms like fever, chills, or unexplained infections, especially if you have a weakened immune system (e.g., from HIV/AIDS, chemotherapy, or long-term steroid use), recent surgery, or a history of fungal infections.

How the Test Works

Blood is drawn and analyzed using an immunoassay method to identify the fungal antigens. This helps confirm a diagnosis of invasive candidiasis, which can be life-threatening if untreated.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood-thinning medication or have a history of bleeding issues, let your provider know.

Reference range

NegativeN/A

Specimen: serum

No special preparation required

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate a high likelihood of *Candida* infection in the bloodstream, which requires immediate medical attention. Negative results mean no detectable antigens, but further testing (e.g., cultures) may still be needed to rule out infection or guide treatment decisions.

Short name

Candida Antigen Test

Frequently asked questions

Why might my doctor order this test?
Your doctor may order this test if you have symptoms of a serious fungal infection, a weakened immune system, or recent medical procedures that increase your risk of infection.
What does a positive result mean?
A positive result suggests a possible *Candida* bloodstream infection, which may require antifungal medications. Further testing and medical evaluation will determine the next steps.
Can I get this test at home?
No, this test is typically done in a clinical lab using blood drawn by a healthcare professional. Home tests for fungal infections are not standard.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy