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Candida antigen in serum (quantitative)

Published: August 9, 2026Updated: August 15, 2026

This test measures the presence of antigens from *Candida* yeast in your blood serum. It helps detect infections caused by *Candida* fungi, which can occur in immune-compromised individuals or after certain medical procedures.

Quick summary

["This test helps identify fungal infections early, even when symptoms aren’t obvious."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
109177-6
Short code
CANDIGA
Synonyms
Candida IgA Msmt Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Ref low
0
Ref high
10
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA)
CPT
86645
SNOMED
423100009
Specimen volume
1-2 mL of serum
Stability
Stable for 7 days at 2-8°C; stable for 30 days at -20°C or below
Hemolysis max
100
Lipemia max
50
Icterus max
50
TAT
24–72 hours
Order
routine

What Is This Test Measuring?

The test detects specific proteins (antigens) produced by *Candida* yeast, which can be released into your blood during an infection. This helps distinguish *Candida* infections from other causes of bloodstream infections.

Why Might You Need This Test?

Your healthcare provider may order this test if you have risk factors for *Candida* infections, such as weakened immunity, recent surgery, or prolonged use of antibiotics or intravenous medications.

When Might Results Be Abnormal?

Elevated results suggest an active *Candida* infection, but false positives can occur. Results alone aren’t diagnostic; they’re often used alongside clinical findings and other tests.

What Does It Mean If Results Are Abnormal?

High levels may indicate a systemic *Candida* infection, prompting treatment with antifungal medications. Follow-up tests may be needed to confirm the diagnosis and monitor response to treatment.

Reference range

Negative: <10 U/mL; Borderline: 10-15 U/mL; Positive: >15 U/mLN/A

Specimen: serum

No special preparation required. Sample can be collected at any time of day.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a key role in diagnosing *Candida* bloodstream infections in high-risk patients, particularly those with signs of sepsis or unexplained fever. It can help guide early antifungal therapy to improve outcomes.

Short name

Candida antigen test

Frequently asked questions

Why was I asked to provide a blood sample for this test?
Blood samples are drawn to detect *Candida* antigens in your serum, which can’t be seen under a microscope. This method is more sensitive than culture tests for some patients.
Can I eat or drink before this test?
No special preparation is needed, but avoid alcohol for 24 hours before your blood draw to reduce potential interference.
Will this test show all types of *Candida* infections?
This test detects common *Candida* species but may not cover all strains. Results should be interpreted by your provider in the context of your symptoms and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy