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Candida Antigen Quantitative (Serum/Plasma)

Published: August 9, 2026Updated: August 15, 2026

This test measures the presence of certain proteins produced by *Candida* yeast in your blood. It helps doctors check for active *Candida* infections, such as bloodstream or invasive infections.

Quick summary

["Assists in diagnosing or monitoring *Candida* infections, especially in high-risk patients."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
9498-7
Short code
CANDIGA
Synonyms
Candida IgA Ser-aCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacuum tube
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA)
CPT
86628
SNOMED
31323009
Specimen volume
1-2 mL of serum
Stability
Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

What This Test Measures

The test detects *Candida* antigens—specific proteins released when *Candida* yeast grows in your blood. These proteins are not found in healthy individuals, making them useful for identifying active infections. The test is particularly useful for detecting *Candida* bloodstream infections, which can be life-threatening if untreated.

When You Might Need This Test

Your doctor may order this test if you have symptoms like fever, chills, or unusual fatigue, especially if you have a weakened immune system (e.g., from chemotherapy, HIV, or organ transplant). It’s also used in patients with prolonged hospital stays or central venous catheters, as these increase infection risk.

How the Test Works

A blood sample is taken and analyzed using a sensitive immunoassay method to detect the presence of *Candida* antigens. This method can detect very small amounts of these proteins, even when infection signs are subtle.

Preparation for the Test

No special preparation is needed. You may have a small needle inserted to draw blood from your arm. If you’re on blood-thinning medication, let your doctor know before the test.

Reference range

Reference ranges vary by laboratory and assay manufacturer; generally negative or <1:10 titer considered normal. Positive results may indicate past or current Candida infection.N/A

Specimen: serum

No special preparation required. Sample can be collected at any time of day. Patient should inform clinician of any immunosuppressive medications or recent antibiotic/antifungal therapy that may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Candida Antigen Level

Frequently asked questions

Could I have symptoms of a *Candida* infection but still test negative?
Yes, infections may not always show symptoms early, and some cases may be too mild to trigger detectable antigen levels. Your doctor may recommend follow-up tests or additional monitoring if needed.
Is this test the same as a *Candida* blood culture?
No, this test detects antigens (proteins) produced by *Candida* yeast, while a blood culture grows yeast cultures in a lab to confirm infection. Both tests are useful but serve different purposes.
How long will results take?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy