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Candida IgG Immunoassay (Serum/Plasma)

Published: August 9, 2026Updated: August 15, 2026

This test measures your body’s immune response to *Candida* yeasts, which can live in your mouth, gut, or skin. It helps determine if you’ve been exposed to these organisms, though it doesn’t confirm an active infection.

Quick summary

["This test helps assess past exposure to *Candida* yeasts, not current infection status."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
40825-2
Short code
CANDG
Synonyms
Candida IgG Titr Ser
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant
Units
N/A
Ref low
0
Ref high
1
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme Immunoassay (EIA) or Immunofluorescence Assay (IFA) for detection and titration of Candida-specific IgG antibodies
CPT
86645
SNOMED
122559005
Specimen volume
1-2 mL of serum (minimum 0.5 mL)
Stability
Serum stable at room temperature for 8 hours; refrigerated at 2-8°C for 7 days; frozen at -20°C or below for up to 30 days; avoid repeated freeze-thaw cycles
Hemolysis max
200
Lipemia max
100
Icterus max
20
TAT
48–120 hours
Order
routine

What Does This Test Measure?

The test detects antibodies (IgG) your immune system produces in response to *Candida* yeasts. These antibodies indicate prior exposure, but they don’t prove whether you have an active infection. The presence of these antibodies suggests your body has encountered *Candida* at some point, possibly from ingestion, skin contact, or other routes.

Why Might You Need This Test?

Doctors may order this test if you have symptoms like persistent mouth sores, skin rashes, or digestive issues that could suggest *Candida* exposure, especially if you’ve had recent antibiotic use, weakened immunity, or other risk factors. It’s also sometimes used in research or monitoring for certain conditions.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The blood is sent to a lab, where it’s tested for IgG antibodies against *Candida* using an immunoassay method. This process typically takes a few days to complete.

What Are Possible Results?

Results are qualitative (positive or negative) and indicate whether detectable IgG antibodies were found. A positive result suggests past exposure, but it doesn’t confirm an active infection. A negative result means no detectable antibodies were found, though this doesn’t rule out past exposure.

Reference range

Titer <1:160 (Negative); Titers vary by laboratory method. Generally, titers ≥1:160 suggest prior exposure or colonization; significantly elevated titers (≥1:640) may indicate systemic or invasive candidiasisN/A

Specimen: serum

No special patient preparation required. Specimen should be collected prior to administration of antifungal therapy when possible, as treatment may affect antibody titers

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to Candida

Frequently asked questions

How Does This Test Help Your Doctor?
This test can help identify if you’ve been exposed to *Candida* yeasts, which may be relevant if you have symptoms or risk factors for *Candida* infections. However, it’s not a diagnostic tool for active infections. Your doctor will consider the test result alongside other symptoms, medical history, and possibly additional tests to determine the best course of action.
What Does a Positive Result Mean?
A positive result means your immune system has likely encountered *Candida* yeasts before. This could be due to exposure through diet, skin contact, or other means. It doesn’t mean you currently have an infection, but it may warrant further evaluation if you have symptoms suggestive of *Candida* involvement.
What If My Test Result Is Negative?
A negative result means no detectable IgG antibodies were found, suggesting you haven’t been exposed to *Candida* in a way that triggered an immune response. However, this doesn’t guarantee you’ve never encountered *Candida*. If you have symptoms, your doctor may recommend other tests or further evaluation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy