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Candida Antigen in Serum (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of Candida antigens in your blood, which can help identify an active fungal infection caused by yeast of the Candida genus.

Quick summary

["This test helps diagnose infections like candidiasis, often seen in weakened immune systems or after medical procedures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88717-4
Short code
CANDID
Synonyms
Candida Islt
Category
chemistry
Sample
serum
Container
Sterile, leak-proof container appropriate for specimen type (e.g., blood culture bottles for blood; sterile cup for urine, sputum, or wound specimens). For serum, use serum separator tube (SST) or red-top tube.
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Culture identification; microscopy with Gram stain; biochemical/automated identification systems (e.g., VITEK 2, MALDI-TOF MS); DNA sequencing or PCR confirmation when required
CPT
87081
SNOMED
10828004
Specimen volume
1-10 mL depending on specimen type; blood culture bottles typically require 8-10 mL per set (aerobic and anaerobic). For serum, minimum 1 mL.
Stability
Specimens should be transported to the laboratory as soon as possible. Blood culture bottles: room temperature, process within 2 hours or per manufacturer instructions (up to 24 hours). Serum: stable at room temperature for 2-4 hours, refrigerated (2-8°C) for up to 7 days. Tissue and fluid specimens: refrigerated, process within 24 hours.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–168 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms such as fever, persistent mouth or throat sores, or signs of infection in areas like the blood, lungs, or urinary tract. It’s also used in patients with conditions that weaken immunity, such as HIV/AIDS, cancer, or those undergoing chemotherapy.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you may feel a brief pinch. Avoid alcohol for 24 hours before the test if instructed.

What the Test Results Mean

A positive result indicates the presence of Candida antigens, suggesting an active infection. A negative result means no detectable antigens were found, but further testing may still be needed to rule out other causes of symptoms.

Common Conditions This Test Helps Diagnose

This test is particularly useful for diagnosing invasive candidiasis, which can affect deeper tissues or organs. It’s often used in patients with severe or persistent infections, especially those with compromised immune systems.

Reference range

Not Applicable (Qualitative/Presence-based reporting). Result reported as 'Candida species identified' or 'No Candida species isolated' with specific species noted (e.g., C. albicans, C. glabrata, C. tropicalis, C. parapsilosis, C. krusei). Antifungal susceptibility reported separately if ordered.N/A

Specimen: serum

No special patient preparation required. Fasting is not required. For blood cultures, sample should be collected prior to initiation of antifungal therapy whenever possible. For other specimen types (urine, wound, sputum), standard collection protocols apply.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Candida Antigen Test

Frequently asked questions

How soon will I get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I have this test if I’m pregnant?
Yes, this test can be performed during pregnancy if medically necessary. However, it’s important to discuss any potential risks or benefits with your healthcare provider, as Candida infections can affect pregnancy.
What if my results are positive?
A positive result means you likely have an active Candida infection. Your doctor will work with you to determine the best treatment plan, which may include antifungal medications tailored to your specific needs.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy