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Candida antigen in vaginal fluid (qualitative probe)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of Candida antigens in your vaginal fluid to help identify if you have a vaginal yeast infection caused by *Candida* organisms.

Quick summary

["A positive result may indicate an active yeast infection needing treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47000-5
Short code
CANDVR
Synonyms
Candida rRNA Vag Ql Probe
Category
chemistry
Sample
serum
Container
Viral transport medium (VTM), nucleic acid transport medium, or sterile container as specified by the testing platform
Units
N/A
Fasting
false
Population
adult
Sex
female
Age range
≥ 14 years
Method
probe
CPT
87481
SNOMED
122065001
Specimen volume
1-2 mL of vaginal fluid in appropriate transport medium
Stability
Room temperature: 24-48 hours; Refrigerated (2-8°C): 5-7 days; Frozen (-20°C or below): 30 days (verify with specific assay manufacturer)
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What This Test Measures

The test uses a probe to detect specific antigens produced by *Candida* yeast in your vaginal fluid. These antigens are unique to certain *Candida* species and help confirm the presence of an infection.

How the Test Works

The sample is collected via a swab of vaginal fluid, which is then analyzed using a qualitative immunoassay (probe-based test). This method detects fungal antigens without measuring exact quantities.

When You Might Need This Test

Your healthcare provider may recommend this test if you have symptoms like unusual vaginal discharge, itching, or discomfort, especially if other tests (like a culture) are inconclusive or unavailable.

Symptoms to Watch For

Common symptoms of a vaginal yeast infection include white or thick discharge, itching, redness, or burning during urination or sex. If you experience these, discuss them with your doctor.

Reference range

Negative (Candida species rRNA not detected). Positive results indicate the presence of Candida ribosomal RNA in the specimen.N/A

Specimen: serum

Patient should avoid douching, vaginal medications, creams, or sexual intercourse for at least 24-48 hours prior to specimen collection. Specimen should be collected prior to initiation of antifungal therapy when possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result strongly suggests a *Candida* infection, which can be treated with antifungal medications. A negative result means no detectable antigens, but other causes of vaginal irritation (like bacteria or allergies) could still be present. Follow-up may include additional testing or treatment plans.

Short name

Vaginal fungal infection screening

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have recurrent symptoms of vaginal itching or discharge, if other tests (like a wet mount or culture) were unclear, or if you’re at higher risk for yeast infections (e.g., due to diabetes, pregnancy, or recent antibiotic use).
What does a positive result mean?
A positive result means your vaginal fluid contains detectable *Candida* antigens, strongly suggesting a yeast infection. Your doctor will likely prescribe antifungal treatment to clear the infection.
Can I still have a yeast infection if the test is negative?
Yes, a negative result means no detectable antigens, but other factors (like bacterial overgrowth or irritation) could still cause symptoms. Your doctor may recommend further testing or treatment based on your symptoms and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy