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Candida Antigen Detection (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of Candida antigens in your blood, helping detect serious fungal infections caused by *Candida* yeasts, such as invasive candidiasis.

Quick summary

["Checks for bloodstream fungal infections that may require urgent medical attention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92724-4
Short code
VAGDNA
Synonyms
Candida sp + GV + TV DNA Pnl Vag Probe
Category
chemistry
Sample
serum
Container
Viral transport medium or specific Aptima collection kit (Hologic) for vaginal fluid specimens
Units
N/A
Fasting
false
Population
adult
Sex
female
Age range
12–99 years
Method
probe
CPT
87481
SNOMED
43491000
Specimen volume
1-2 mL of vaginal fluid in transport medium
Stability
Room temperature: 14 days; Refrigerated (2-8°C): 30 days; Frozen (-70°C): 6 months
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, chills, or unexplained infections, especially after undergoing medical procedures (e.g., central lines, surgeries) that increase risk. It’s also used in patients with weakened immune systems or those with prolonged hospital stays.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your vein (venipuncture) to draw blood. The process usually takes a few minutes.

What the Results Mean

Positive results indicate the presence of Candida antigens, suggesting an active infection. Negative results mean no detectable antigens were found, but further testing or observation may still be needed.

Common Causes of Positive Results

Positive results are most common in patients with invasive candidiasis (e.g., bloodstream, organ infections) or those with risk factors like diabetes, cancer, or recent antibiotic use.

Reference range

Negative for Candida sp, Gardnerella vaginalis, and Trichomonas vaginalis DNAN/A

Specimen: serum

Patient should avoid vaginal douching, intercourse, and use of vaginal medications for at least 24-48 hours prior to specimen collection. Ideally specimen should be collected prior to menses or after menstrual flow has ceased.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Urgent Evaluation Needed

Short name

Candida Antigen Test

Frequently asked questions

A positive result signals a fungal infection that requires prompt treatment with antifungal medications. Delayed action can worsen outcomes, especially in immunocompromised patients.
This test helps confirm infections that standard blood cultures may miss, guiding treatment decisions to prevent complications like organ failure.
FAQ 1: Can I eat or drink before the blood draw?
Yes, you can eat and drink normally unless instructed otherwise. No fasting is required.
FAQ 2: Are there any risks with this test?
Minor risks include bruising, slight pain, or a small swelling at the injection site. Rarely, allergic reactions or infection may occur, but these are uncommon.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy