Candida species (fungal) detection by quantitative real-time polymerase chain reaction (PCR) in whole blood
This test checks for the presence of Candida fungi in your blood using a sensitive genetic test. It helps identify infections caused by yeast-like fungi that can affect the bloodstream, often in people with weakened immune systems.
["A blood test to detect fungal infections quickly, especially in high-risk patients."]
Key facts at a glance
- LOINC
- 106411-2
- Short code
- CANDBC
- Synonyms
- Candida spp. 2 DNA Ct Bld +Qn NAA+prb
- Category
- chemistry
- Sample
- whole-blood
- Container
- Positive blood culture bottle (aerobic and/or anaerobic) identified as positive by continuous-monitoring blood culture system
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 0–120 years
- Method
- probe-amp-tar
- CPT
- 87481
- SNOMED
- 122460008
- Specimen volume
- 1-3 mL aliquot from positive blood culture bottle
- Stability
- Process positive blood culture broth within 24 hours of positivity flag; extracted DNA stable at 2-8°C for 24 hours or frozen at -70°C for extended storage
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 2–8 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like fever, chills, or unexplained infections, or if you’re at higher risk for bloodstream fungal infections. This could include people with cancer, undergoing chemotherapy, having organ transplants, or with severe immune deficiencies.
How the Test Works
The test uses a small sample of your whole blood to detect genetic material (DNA) from Candida species. This is done through a highly sensitive PCR process that can detect even tiny amounts of fungus in your bloodstream.
Preparation for the Test
No special preparation is needed for this blood test. You may have a standard blood draw, similar to other routine tests. Your provider will explain the process and any potential discomfort.
What to Expect After the Test
After the blood sample is taken, it will be sent to a lab for analysis. Results are typically available within a few days. If the test finds Candida DNA, it suggests a possible fungal infection that may need further medical evaluation.
Reference range
Not applicable - qualitative identification reported as Detected or Not Detected. Cycle threshold (Ct) value is reported for positive results to indicate relative organism burden; lower Ct values correspond to higher fungal load.N/A
No special patient preparation required. Specimen should be collected prior to initiation of antifungal therapy when possible to maximize diagnostic yield. Standard aseptic technique for blood culture collection is essential to prevent contamination.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Candida PCR Blood Screen
Frequently asked questions
This test is particularly useful for identifying bloodstream fungal infections early, which can be life-threatening if untreated. It helps healthcare providers quickly determine if antifungal treatment is needed, especially in patients who are at higher risk of severe infections.
A positive result indicates the presence of Candida species DNA in your blood. This does not necessarily mean you have an active infection yet, but it signals a need for further evaluation by your healthcare provider. They may recommend additional tests or treatments to address the potential infection.
Results are usually available within 2 to 5 business days, depending on lab processing times. Your healthcare provider will contact you directly to discuss the results and next steps.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy