Skip to content

Carbamazepine concentration in serum/plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of carbamazepine, a medication used to treat certain types of seizures and nerve pain, in your blood.

Quick summary

["Your blood carbamazepine level helps doctors monitor your dose for safety and effectiveness."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
59876-3
Short code
CRBMZ-GF
Synonyms
carBAMazepine Gast Ql
Category
chemistry
Sample
serum
Container
Sterile, leak-proof plastic container (gastric aspirate collection container); red-top or green-top sodium heparin tube for serum
Units
N/A
Ref low
4
Ref high
12
Critical range
— – 15 N/A
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Immunoassay or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
80335 (Gas chromatography/mass spectrometry) or 80329 (immunoassay)
SNOMED
387207008
Specimen volume
5-10 mL of gastric fluid
Stability
Room temperature: 2 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
1–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking carbamazepine to manage conditions like epilepsy, bipolar disorder, or trigeminal neuralgia. It helps ensure your dose stays within safe levels and avoids side effects, such as dizziness or drowsiness.

How the Test Works

A blood sample is taken from a vein in your arm. The sample is then analyzed using a specialized lab test to measure carbamazepine levels in your blood plasma or serum.

What to Expect Before the Test

No special preparation is needed, but you may want to drink plenty of water the day of the test. If you’re on other medications, let your provider know—some drugs can affect carbamazepine levels.

Possible Results and Interpretation

Results are typically reported as a concentration (e.g., micrograms per milliliter). Your provider will compare these results to your specific dose and medical needs to adjust your treatment if needed.

Reference range

Not applicable for qualitative presence testing; therapeutic serum reference range typically 4-12 mcg/mLN/A

Specimen: serum

No fasting required. Specimen is typically collected in suspected overdose or poisoning cases via gastric lavage or aspiration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Carbamazepine Level

Frequently asked questions

What does a low carbamazepine level mean?
Low levels may indicate your body is breaking down the medication too quickly, which could reduce its effectiveness. Your provider might suggest adjusting your dose or adding a different medication to help maintain steady levels.
What does a high carbamazepine level mean?
High levels can increase the risk of side effects like dizziness, confusion, or rash. Your provider may lower your dose or monitor you closely to prevent toxicity.
How often should I get this test?
Your provider will determine how often you need testing based on your condition, dose, and how your body responds to the medication. Follow their instructions to avoid unnecessary tests or risks.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy