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Carbamazepine concentration (serum/plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of carbamazepine, a medication used to treat certain types of seizures or nerve pain, in your blood.

Quick summary

["Your doctor may check this level to ensure you’re taking the right dose and to avoid side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
96277-9
Short code
CARBAMIGE
Synonyms
carBAMazepine IgE Qn
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant
Units
N/A
Ref low
0.1
Ref high
0.35
Critical range
— – 15 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Immunoassay (e.g., FEIA/Fluorescence Enzyme Immunoassay or CLIA/Chemiluminescent Immunoassay)
CPT
86003
SNOMED
39579005
Specimen volume
1 mL serum (minimum 0.5 mL)
Stability
Stable at room temperature for 8 hours; refrigerated (2-8°C) for 7 days; frozen (-20°C) for up to 30 days; avoid repeated freeze-thaw cycles
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why This Test Matters

Carbamazepine helps control seizures or nerve-related symptoms, but too much or too little can cause problems. This test helps doctors monitor your dose and adjust it safely.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re on this medication, your doctor may suggest timing the test around when you take your dose.

How the Test Works

A lab technician uses a sensitive test to measure carbamazepine in your blood. The result tells your doctor how much of the drug is in your system at that time.

Possible Results and Next Steps

Your doctor will compare your result to what’s typical for your dose and health. If levels are too high or too low, they may change your medication or monitor you more closely.

Reference range

Negative: <0.10 kU/L; Equivocal/Borderline: 0.10-0.35 kU/L; Positive: >0.35 kU/L (Class 1-6 classification may apply per assay)N/A

Specimen: serum

No special preparation required. Patient should inform provider of all current medications including antihistamines, though discontinuation is generally not required for IgE testing

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Carbamazepine levels can affect how well it works or cause side effects like dizziness, drowsiness, or skin rashes. Low levels might mean your dose isn’t strong enough, while high levels could signal toxicity.

Short name

Carbamazepine Level

Frequently asked questions

When might I need this test?
Your doctor may order this test if you’re newly prescribed carbamazepine, if you’re having side effects, or if your symptoms aren’t improving. They might also check it regularly if you’re on long-term use.
What does a ‘normal’ result mean?
There’s no single ‘normal’ range for everyone—it depends on your dose, health, and how your body processes the drug. Your doctor will use your specific result to guide care.
Can I eat or drink before the test?
You can usually eat and drink normally unless your doctor says otherwise. Some medications (like grapefruit juice) can affect carbamazepine levels, so check with them if you’re unsure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy