Carbamazepine concentration (serum/plasma)
This test measures the amount of carbamazepine, a medication used to treat certain types of seizures or nerve pain, in your blood. It helps your healthcare provider check if your dose is working properly and adjust it as needed.
["Your carbamazepine levels help ensure safe and effective dosing for seizure control or pain management."]
Key facts at a glance
- LOINC
- 73049-9
- Short code
- CBZ-NAB
- Synonyms
- carBAMazepine (neut) IgM SerPl Ql FC
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red top tube
- Units
- N/A
- Ref low
- 4
- Ref high
- 12
- Critical range
- — – 15 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 86021
- SNOMED
- 395112001
- Specimen volume
- 2-5 mL of whole blood; minimum 1 mL serum
- Stability
- Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
Why This Test Matters
Carbamazepine is a prescription drug that works by stabilizing electrical activity in the brain. It’s often prescribed for epilepsy or conditions like trigeminal neuralgia. Blood levels are monitored to prevent side effects (like dizziness, drowsiness, or rare but serious blood disorders) while ensuring it remains effective. Your provider may order this test if you’re starting carbamazepine, adjusting your dose, or experiencing symptoms that might indicate the medication isn’t working as intended.
What to Expect Before the Test
No special preparation is usually needed. You’ll have a small needle inserted into a vein (most often in your arm) to draw blood. This is quick and typically painless. If you’re on other medications that interact with carbamazepine (like certain antibiotics or birth control), let your provider know before testing.
What the Results Mean
Results are compared to a general reference range, but individual needs vary. Low levels may mean the medication isn’t working well, while very high levels could signal toxicity. Your provider will discuss your specific results and any needed adjustments with you.
Common Reasons for Testing
Your doctor might order this test if you’re taking carbamazepine to manage seizures or nerve pain. It’s also used to monitor long-term therapy, check for interactions with other drugs, or assess whether your body is processing the medication as expected.
Reference range
Therapeutic: 4-12 mcg/mLN/A
No special patient preparation required. Patient should be on carbamazepine therapy or have recent exposure history documented. Inform laboratory of medication history and suspected adverse drug reaction.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Carbamazepine Level
Frequently asked questions
What causes false or misleading results in this test?
How long does it take to get results?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy