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Carbamazepine Concentration (Serum/Plasma)

Published: August 9, 2026Updated: August 15, 2026

This test measures the amount of carbamazepine, a medication used to treat certain types of seizures and nerve pain, in your blood.

Quick summary

["Your doctor may check this level to ensure the drug is working properly and to avoid harmful side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
35237-7
Short code
CARB
Synonyms
carBAMazepine SerPl-msCnc
Category
chemistry
Sample
serum
Container
Red-top serum tube (no anticoagulant) or serum separator tube (SST/gold-top)
Units
N/A
Ref low
4
Ref high
12
Critical range
— – 15 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (e.g., chemiluminescent immunoassay, fluorescence polarization immunoassay) or Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT
80156
SNOMED
1026991000119102
Specimen volume
1.0–2.0 mL of serum
Stability
Room temperature: 8 hours. Refrigerated (2–8°C): 48 hours. Frozen (-20°C or below): 4 weeks. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
30
TAT
1–4 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking carbamazepine to manage conditions like epilepsy, bipolar disorder, or trigeminal neuralgia. It helps monitor your dose to balance effectiveness and safety.

What Does the Test Involve?

A blood sample is taken from a vein in your arm. The sample is sent to a lab where it’s analyzed to measure carbamazepine levels using a specialized test method.

What Does the Result Mean?

Results aren’t provided with specific reference ranges here, as they depend on your individual needs and the dose prescribed. Your doctor will interpret the result in relation to your treatment plan.

What Are Possible Side Effects?

Carbamazepine can cause side effects like dizziness, drowsiness, or gastrointestinal upset. Rarely, it may affect blood cells or cause serious allergic reactions. Always report unusual symptoms to your doctor.

Reference range

Therapeutic range: 4.0–12.0 mcg/mL (or mg/L). Optimal target levels may vary based on clinical indication, patient response, and concomitant medications.N/A

Specimen: serum

No fasting required. Trough levels should be drawn immediately before the next scheduled dose (typically in the morning). Document the time of last dose and sample collection time on the requisition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Carbamazepine Level

Frequently asked questions

What If My Level Is Too High?
High levels may indicate overdose or improper metabolism, increasing risk of toxicity. Your doctor may adjust your dose or monitor you more closely.
What If My Level Is Too Low?
Low levels may mean the drug isn’t working as intended. Your doctor might increase your dose or check for interactions with other medications.
How Often Should I Get This Test?
Your doctor will determine the frequency based on your treatment plan, but it’s often done every few weeks or months to ensure safe and effective dosing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy