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Carbamazepine Serum Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 14, 2026

This test measures the amount of carbamazepine, a medication used to treat certain types of seizures and nerve pain, in your blood serum.

Quick summary

["Your doctor may order this test to check if your carbamazepine levels are within the safe range for your treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 14, 2026Editorial policy

Key facts at a glance

LOINC
35599-0
Short code
CARB
Synonyms
carBAMazepine SerPl Scn-mCnc
Category
chemistry
Sample
serum
Container
Red-top serum separator tube or red-top plain tube (no anticoagulant)
Units
N/A
Ref low
4
Ref high
12
Critical range
— – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
CPT
80157
SNOMED
387161007
Specimen volume
1-2 mL of serum
Stability
Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
100
Lipemia max
500
Icterus max
25
TAT
2–8 hours
Order
routine

Why This Test Is Done

Your healthcare provider may request this test if you’re taking carbamazepine to manage epilepsy or another condition. It helps ensure the drug is working effectively and at a safe level in your body.

What to Expect Before the Test

No special preparation is needed. You’ll typically have a small needle inserted into your arm or vein to draw blood. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Results show how much carbamazepine is present in your blood. While reference ranges vary by lab, they help determine if your dose is too high or too low. Your doctor will interpret these results in the context of your treatment plan.

Common Reasons for Monitoring

Regular monitoring helps prevent side effects like dizziness, drowsiness, or rare but serious issues like low blood cell counts. It also ensures the drug remains effective over time.

Reference range

Therapeutic range: 4-12 mcg/mL; Toxic: >15 mcg/mLN/A

Specimen: serum

No fasting required. Trough levels should be drawn immediately before the next scheduled dose for accurate therapeutic drug monitoring

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Carbamazepine levels can fluctuate due to factors like diet, other medications, or how your body processes the drug. Your doctor may adjust your dose based on these results to balance safety and effectiveness.

Short name

Carbamazepine Level

Frequently asked questions

What happens if my carbamazepine levels are too high?
High levels may cause symptoms like nausea, confusion, or rapid heartbeat. If detected, your doctor will adjust your dose or monitor you closely until levels return to a safer range.
Can food affect this test?
Some foods or supplements may interact with carbamazepine, potentially altering your blood levels. Your doctor will discuss dietary or lifestyle changes if needed.
How often will I need this test?
Frequency depends on your treatment plan. Some patients need regular checks (e.g., every few weeks), while others may only need it periodically based on symptoms and lab trends.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 14, 2026. · Read our editorial policy