Skip to content

Carbapenemase Detection by Rapid Immunochromatographic Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of carbapenemase enzymes, which are bacteria-produced proteins that can make certain antibiotics ineffective. It helps determine if a bacterial infection may be resistant to carbapenem antibiotics, which are used for serious infections.

Quick summary

["Identifies potential antibiotic resistance in bacterial infections that may require alternative treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101672-4
Short code
Carbapenemase pnl Islt IA.rapid
Synonyms
Carbapenemase pnl Islt IA.rapid
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia-rapid
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have a suspected infection caused by bacteria that could produce carbapenemases, especially if you’ve been exposed to carbapenem antibiotics. It’s also used in monitoring patients with known or suspected infections involving resistant bacteria, such as those in intensive care units or with healthcare-associated infections.

How the Test Works

The test uses a rapid immunoassay (a type of antibody test) on a small sample of your serum or plasma. It detects specific proteins (carbapenemases) that bacteria produce to break down carbapenem antibiotics. Results are typically available within 30 minutes.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is processed to separate the serum or plasma, which is then tested. No special preparation is needed, but fasting may not be required unless specified by your provider.

What to Expect During and After the Test

You’ll likely feel minor discomfort from the needle insertion, but most people tolerate it well. After the test, you may experience a small bruise or swelling at the injection site, which usually fades within a few days. No special follow-up is needed unless your provider advises otherwise.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate the presence of carbapenemase-producing bacteria, which can lead to infections resistant to carbapenem antibiotics. This information is critical for guiding appropriate antibiotic treatment, reducing the risk of further spread of resistant bacteria, and preventing unnecessary use of ineffective antibiotics. Early identification helps prevent complications and ensures you receive the most effective therapy.

Short name

Carbapenemase Screen (Serum/Plasma)

Frequently asked questions

What does a positive result mean?
A positive result suggests that the bacteria in your sample may produce carbapenemases, meaning they could be resistant to carbapenem antibiotics. Your healthcare provider will discuss the next steps, which may include adjusting your treatment plan or starting alternative antibiotics.
Can this test be done on other body fluids?
This test is primarily performed on serum or plasma from blood samples. However, if your infection involves other fluids (like urine or cerebrospinal fluid), your provider may use a different test or sample type to detect carbapenemases.
How soon will I get my results?
Results are typically available within 30 minutes after the test. Your healthcare provider will contact you to discuss the findings and any next steps, such as further testing or treatment adjustments.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy