Cardiolipin Antibody (IgG) Test
This test measures the presence of antibodies against cardiolipin, a phospholipid found in cell membranes. These antibodies may be linked to certain autoimmune conditions and blood clotting disorders.
["This test helps assess potential autoimmune or clotting-related risks."]
Key facts at a glance
- LOINC
- 24319-6
- Short code
- CARDIP
- Synonyms
- Cardiolipin IgG+IgM Pnl Ser
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube
- Units
- N/A
- Ref low
- 0
- Ref high
- 10
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme-Linked Immunosorbent Assay (ELISA)
- CPT
- 86147
- SNOMED
- 4445-6
- Specimen volume
- 1.0 mL serum (minimum 0.5 mL)
- Stability
- Room temperature: 8 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 24–72 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms or risk factors for conditions like lupus, antiphospholipid syndrome, or other autoimmune diseases. It may also be used to monitor these conditions over time.
What Does a Positive Result Mean?
A positive result indicates the presence of cardiolipin antibodies in your blood. While this can be associated with autoimmune disorders or increased risk of blood clots, it does not always mean you have a specific condition. Further evaluation by your doctor may include additional tests or monitoring.
What to Expect Before the Test
No special preparation is usually needed. You may have a blood sample drawn from a vein in your arm. If you are on blood thinners or have recently had a procedure involving blood, inform your healthcare provider before the test.
What Happens During the Test?
A healthcare professional will collect a small amount of blood from a vein in your arm. The blood will be sent to a lab for analysis using an immunoassay method to detect cardiolipin antibodies.
Reference range
IgG: Negative <10 GPL U/mL; Equivocal 10-40 GPL U/mL; Positive >40 GPL U/mL. IgM: Negative <10 MPL U/mL; Equivocal 10-40 MPL U/mL; Positive >40 MPL U/mLN/A
No special patient preparation required. Fasting is not necessary.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Cardiolipin Antibodies and Health Implications
Short name
IgG Anti-Cardiolipin Antibody
Frequently asked questions
What are cardiolipin antibodies?
Can this test diagnose a specific condition?
Are there any risks or side effects?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy