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Carotene [Mass/volume] in Whole Blood

Published: August 9, 2026Updated: August 10, 2026

This test measures the amount of carotene in whole blood. Carotene is a pigment found in foods such as carrots, leafy greens, and other colorful fruits and vegetables.

Quick summary

["The result can help assess carotene levels, but diet, supplements, illness, and laboratory methods can affect interpretation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 10, 2026Editorial policy

Key facts at a glance

LOINC
2052-9
Short code
CAROT
Synonyms
Carotene Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Red-top serum separator tube (SST) or plasma separator tube (PST) with heparin; protect from light
Units
N/A
Ref low
60
Ref high
200
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
High-Performance Liquid Chromatography (HPLC) with UV detection
CPT
82380
SNOMED
8691008
Specimen volume
3-5 mL whole blood (minimum 1 mL serum or plasma)
Stability
Stable for 4 hours at room temperature; 2 weeks at 2-8°C when protected from light; 1 year at -20°C when protected from light. Specimen must be wrapped in aluminum foil to prevent photodegradation.
Hemolysis max
50
Lipemia max
100
Icterus max
20
TAT
24–72 hours
Order
routine

What This Test Measures

The test quantifies carotene circulating in whole blood. Carotene comes mainly from the diet and is associated with fat-soluble vitamin intake, although blood levels do not directly measure every aspect of nutrition.

Why the Test May Be Ordered

A clinician may order this test when nutritional status is unclear, particularly in a person with a limited or unusual diet, malabsorption concerns, or symptoms that could be related to nutritional deficiencies.

Factors That Affect the Result

Recent changes in fruit and vegetable intake, carotenoid supplements, fat intake, absorption, and illness can change blood carotene levels. Testing methods and sample handling may also affect results.

How to Prepare

Follow the laboratory’s preparation instructions. Ask whether you should continue supplements or maintain a consistent diet before the sample is collected, because these factors can influence the result.

Reference range

Adult: 60-200 µg/dL (0.6-2.0 mg/L); values vary by laboratory methodology and populationN/A

Specimen: whole-blood

No fasting required. However, a fasting sample may be preferred to minimize lipemic interference. Patient should avoid excessive carrot, sweet potato, and leafy green vegetable intake for 24 hours prior to collection for accurate baseline measurement.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: A low whole-blood carotene result may reflect low dietary intake or impaired absorption, while a high result may follow heavy supplement use or a recent increase in carotenoid-rich foods. Results should be interpreted with symptoms, diet, medical history, and other nutritional tests by a qualified clinician.

Short name

Whole Blood Carotene

Frequently asked questions

What is carotene?
Carotene is a group of naturally occurring pigments, including beta-carotene, found in colorful vegetables, fruits, and other foods. It is related to vitamin A and is measured as part of nutritional assessment.
Is fasting required for this test?
Fasting may or may not be recommended depending on the laboratory and clinical situation. Because recent dietary intake affects the result, follow the specific instructions provided before testing.
Does a low result always indicate a vitamin A deficiency?
No. A low carotene level may suggest low intake or poor absorption, but it does not by itself diagnose vitamin A deficiency. Your clinician may consider symptoms, diet, and other laboratory findings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy