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Total Calcium (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of calcium in your blood serum, an essential mineral that plays a key role in muscle function, nerve signaling, and bone health.

Quick summary

["Your blood calcium levels help ensure proper muscle and nerve function and support strong bones."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38437-0
Short code
CASHEW IGE
Synonyms
Cashew nut IgE/IgE total %
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube with clot activator
Units
N/A
Ref low
0
Ref high
0.35
Fasting
false
Population
adult
Sex
all
Age range
≥ 0 years
Method
Fluorescent enzyme immunoassay (FEIA) / ImmunoCAP
CPT
86003
SNOMED
395790002
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Room temperature: 7 days; Refrigerated (2-8°C): 14 days; Frozen (-20°C): 1 year. Avoid repeated freeze-thaw cycles.
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions affecting calcium balance, such as kidney disease, bone disorders, or metabolic issues. It can also help diagnose or monitor symptoms like muscle weakness, bone pain, or abnormal heart rhythms.

What Does It Tell You?

Total calcium levels help identify whether you have hypocalcemia (too little calcium) or hypercalcemia (too much calcium), which can cause various health problems. However, calcium levels alone may not pinpoint the exact cause of symptoms.

How Is It Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure total calcium concentration.

What Are Common Results?

Results are typically reported in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L). While reference ranges vary by lab, they generally fall between 8.5 and 10.2 mg/dL (2.13–5.12 mmol/L). Your actual range may differ slightly.

Reference range

IgE total: <100 IU/mL (adults); Specific IgE: <0.35 kU/L (Class 0 - Negative). Results reported in kU/L with classification: <0.35 (Class 0), 0.35-0.70 (Class 1), 0.70-3.50 (Class 2), 3.50-17.50 (Class 3), 17.50-50.00 (Class 4), 50.00-100.00 (Class 5), >100.00 (Class 6).N/A

Specimen: serum

No special preparation required. Patient should inform provider of any antihistamine or corticosteroid use, though these do not affect IgE antibody levels. Avoid testing during active allergic episodes if possible for baseline assessment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Total calcium levels are crucial for diagnosing conditions like hypoparathyroidism, kidney disease, or hyperparathyroidism. Abnormal levels may also indicate conditions affecting vitamin D metabolism, bone disorders, or certain cancers.

Short name

Total Calcium

Frequently asked questions

What might cause abnormal calcium levels?
Abnormal calcium levels can result from conditions like kidney disease, thyroid disorders, vitamin D deficiency, or certain medications. Lifestyle factors, such as diet or long-term vitamin supplements, may also play a role.
How long does it take to get results?
Results are usually available within 1 to 3 business days, depending on your lab’s processing time and any follow-up tests needed.
Can I eat or drink anything before this test?
You may drink water but avoid caffeine or large amounts of milk/calcium-rich foods for a few hours before the test to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy