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Serum Cholesterol (Total)

Published: August 9, 2026Updated: August 17, 2026

This test measures the total amount of cholesterol in your blood serum. Cholesterol is a type of fat that your body needs for many functions, but high levels can increase your risk of heart disease.

Quick summary

["Check your cholesterol levels to help prevent heart disease and maintain heart health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
103115-2
Short code
Cashew rAna o3 IgE
Synonyms
Cashew nut (rAna o) 3 IgE RAST
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacuum tube; avoid gel separator interference tubes when possible
Units
N/A
Ref low
0
Ref high
0.35
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
0–120 years
Method
Radioallergosorbent test (RAST) detecting IgE antibodies against recombinant cashew nut allergen component rAna o 3 using solid-phase immunoassay with radiolabeled anti-IgE detection
CPT
86003
SNOMED
39579001
Specimen volume
0.5-1.0 mL serum (minimum 0.3 mL); pediatric minimum 0.2 mL
Stability
Serum stable at room temperature for 8 hours; refrigerated at 2-8°C for 7 days; frozen at -20°C or below for up to 6 months. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
24–72 hours
Order
routine

Why This Test Matters

Cholesterol is essential for cell membranes, hormone production, and vitamin D synthesis. However, too much cholesterol in your blood can build up in your arteries, leading to plaque formation and increasing the risk of heart attacks or strokes. Regular cholesterol screening helps doctors monitor your cardiovascular health and guide treatment if needed.

What to Expect Before the Test

No special preparation is usually required, but your doctor may ask you to fast (not eat or drink) for 12 hours before the test. You’ll have a small needle inserted into your arm to draw blood. The process is quick and typically painless.

How the Test Works

Blood is drawn from a vein in your arm and sent to a lab. There, cholesterol is separated from other blood components and measured using a chemical method that detects its presence and concentration.

What the Results Mean

Results are reported as a total cholesterol number (in mg/dL). While specific reference ranges vary by lab, higher-than-normal levels may signal the need for lifestyle changes, diet adjustments, or medication to manage your cholesterol.

Reference range

Negative: <0.35 kU/L; Equivocal: 0.35-0.70 kU/L; Positive: >0.70 kU/L. Results reported as Presence (Detected/Not Detected) with quantitative titer for clinical correlation.N/A

Specimen: serum

No special preparation required. Patient should continue antihistamine use as prescribed, as antihistamines do not interfere with IgE antibody detection. Avoid sample collection during acute anaphylaxis when possible for baseline assessment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Total Cholesterol

Frequently asked questions

How often should I get this test?
Most adults are advised to get a cholesterol test at least once every 4–5 years, or more frequently if you have risk factors like high blood pressure, diabetes, or a family history of heart disease. Your doctor will tailor recommendations based on your health status.
What does a high cholesterol level mean?
A high total cholesterol level (typically above 200 mg/dL) increases your risk of heart disease. It doesn’t always cause symptoms, so regular monitoring is key. Your doctor may recommend lifestyle changes or medications to lower it.
Can diet or exercise change my cholesterol results?
Yes! Eating a heart-healthy diet (low in saturated fats, high in fiber), exercising regularly, and maintaining a healthy weight can significantly improve cholesterol levels. Small, sustainable changes often have the biggest impact.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy