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C-reactive protein (mass concentration) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56210-8
Short code
CATDNGG4
Synonyms
Cat Dander IgG4-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top vacutainer tube
Units
N/A
Ref low
0
Ref high
0.35
Fasting
false
Population
adult
Sex
all
Age range
1–99 years
Method
Immunoassay (ELISA or Fluorescent Enzyme Immunoassay)
CPT
86001
SNOMED
39512008
Specimen volume
0.5-1 mL serum
Stability
Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below; avoid repeated freeze-thaw cycles
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

Why Is This Test Done?

Your doctor may order a CRP test to check for signs of inflammation, monitor chronic conditions (such as rheumatoid arthritis or heart disease), or evaluate how well you’re responding to treatment for an infection or illness.

Common Uses in Healthcare

CRP is commonly used to screen for infections, track autoimmune diseases, or identify risks for conditions like heart disease or certain cancers.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours if your blood is drawn early in the morning for accuracy.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. You may feel a slight pinch, but it usually takes only a few minutes.

Reference range

Reference ranges vary by laboratory and methodology; results typically reported as negative (<0.35 mg/L), equivocal (0.35-0.50 mg/L), or positive (>0.50 mg/L) for allergen-specific IgG4 antibodiesN/A

Specimen: serum

No special patient preparation required. Patient should be well-hydrated prior to venipuncture. Inform clinician of any current antihistamine or immunosuppressive therapy use as it may affect antibody levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated CRP levels often indicate inflammation, infections, or autoimmune activity. While not specific to a single condition, it helps guide treatment decisions and monitor disease progression.

Short name

CRP (Serum/Plasma)

Frequently asked questions

How long does it take to get results?
Results are typically available within 24–48 hours, depending on lab processing times and your healthcare provider’s workflow.
Can diet or exercise affect CRP levels?
Yes, diet, exercise, and stress can influence inflammation levels. Avoiding heavy meals before testing and managing chronic conditions (like obesity or diabetes) may help get more accurate results.
Is CRP the same as a white blood cell count?
No, CRP measures inflammation specifically, while a white blood cell count assesses immune cell levels. Both tests serve different diagnostic purposes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy