Cathepsin G Antibody, Serum
This test looks for antibodies directed against cathepsin G, a protein found in certain white blood cells, in a sample of your serum. Such antibodies are sometimes measured when evaluating certain immune or inflammatory conditions.
["A cathepsin G antibody test checks your blood serum for antibodies against a specific white blood cell protein that can be relevant in some immune and inflammatory disorders."]
Key facts at a glance
- LOINC
- 54016-1
- Short code
- CATGAB
- Synonyms
- Cathepsin G Ab Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Serum separator tube (SST) or red-top tube without anticoagulant
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- Enzyme-linked immunosorbent assay (ELISA) or Multiplex bead-based immunoassay
- CPT
- 83516 (Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; qualitative or semiquantitative, multiple step method)
- SNOMED
- 122572000 |Antibody detection|
- Specimen volume
- 1.0 mL serum (minimum 0.5 mL)
- Stability
- Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
- Hemolysis max
- 100
- Lipemia max
- 100
- Icterus max
- 50
- TAT
- 48–120 hours
- Order
- routine
What This Test Measures
Cathepsin G is an enzyme stored in granules of neutrophils, a type of white blood cell involved in fighting infection and in inflammation. This test detects antibodies in your blood that target cathepsin G. The presence of such antibodies can be a marker that your immune system is reacting against components of your own white blood cells.
Why Your Doctor May Order It
Your healthcare provider may order this test when evaluating certain inflammatory or immune-related conditions, particularly those affecting blood vessels or the lungs. It is often considered alongside other antibody tests to build a fuller picture of what is happening in your immune system. The result is interpreted together with your symptoms, physical exam, and other laboratory findings.
How the Sample Is Collected
The test is performed on serum, the clear liquid part of blood that remains after the blood has clotted. A healthcare professional collects a standard blood sample from a vein in your arm. You generally do not need special preparation unless your provider gives other instructions.
Understanding Your Results
Results are typically reported as positive or negative, or with a measured level, depending on the laboratory. A positive result means these antibodies were detected, but it does not by itself confirm a specific diagnosis. Your provider will interpret the result in the context of your overall health picture and may order additional testing.
Reference range
Negative (antibodies not detected). Positive indicates presence of anti-cathepsin G antibodies.N/A
No special patient preparation required. Fasting is not necessary.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Does a positive cathepsin G antibody result mean I have a specific disease?
Do I need to fast before this blood test?
Can I interpret my own results without a doctor?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy