Skip to content

Cathepsin G Antibody, Serum

Published: August 9, 2026Updated: August 15, 2026

This test looks for antibodies directed against cathepsin G, a protein found in certain white blood cells, in a sample of your serum. Such antibodies are sometimes measured when evaluating certain immune or inflammatory conditions.

Quick summary

["A cathepsin G antibody test checks your blood serum for antibodies against a specific white blood cell protein that can be relevant in some immune and inflammatory disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 15, 2026Editorial policy

Key facts at a glance

LOINC
54016-1
Short code
CATGAB
Synonyms
Cathepsin G Ab Ser Ql
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube without anticoagulant
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Enzyme-linked immunosorbent assay (ELISA) or Multiplex bead-based immunoassay
CPT
83516 (Immunoassay for analyte other than infectious agent antibody or infectious agent antigen; qualitative or semiquantitative, multiple step method)
SNOMED
122572000 |Antibody detection|
Specimen volume
1.0 mL serum (minimum 0.5 mL)
Stability
Stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below. Avoid repeated freeze-thaw cycles.
Hemolysis max
100
Lipemia max
100
Icterus max
50
TAT
48–120 hours
Order
routine

What This Test Measures

Cathepsin G is an enzyme stored in granules of neutrophils, a type of white blood cell involved in fighting infection and in inflammation. This test detects antibodies in your blood that target cathepsin G. The presence of such antibodies can be a marker that your immune system is reacting against components of your own white blood cells.

Why Your Doctor May Order It

Your healthcare provider may order this test when evaluating certain inflammatory or immune-related conditions, particularly those affecting blood vessels or the lungs. It is often considered alongside other antibody tests to build a fuller picture of what is happening in your immune system. The result is interpreted together with your symptoms, physical exam, and other laboratory findings.

How the Sample Is Collected

The test is performed on serum, the clear liquid part of blood that remains after the blood has clotted. A healthcare professional collects a standard blood sample from a vein in your arm. You generally do not need special preparation unless your provider gives other instructions.

Understanding Your Results

Results are typically reported as positive or negative, or with a measured level, depending on the laboratory. A positive result means these antibodies were detected, but it does not by itself confirm a specific diagnosis. Your provider will interpret the result in the context of your overall health picture and may order additional testing.

Reference range

Negative (antibodies not detected). Positive indicates presence of anti-cathepsin G antibodies.N/A

Specimen: serum

No special patient preparation required. Fasting is not necessary.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Does a positive cathepsin G antibody result mean I have a specific disease?
No. A positive result indicates that these antibodies were detected, but it does not confirm any single diagnosis. Many factors influence results, and your provider will consider them along with your symptoms and other tests.
Do I need to fast before this blood test?
In most cases no special preparation is required, but follow any instructions your healthcare provider or the laboratory gives you, since requirements can vary.
Can I interpret my own results without a doctor?
It is not recommended. These results require expert interpretation in the context of your medical history and other findings, so discuss them with your healthcare provider before drawing conclusions.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 15, 2026. · Read our editorial policy