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C-reactive protein, mass concentration (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of C-reactive protein in your blood. CRP is a protein produced by your liver in response to inflammation or infection.

Quick summary

["CRP helps your doctor assess inflammation in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63082-2
Short code
CAYIGG
Synonyms
Cayenne IgG-mCnc
Category
chemistry
Sample
serum
Container
Serum separator tube (SST) or red-top tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
Immunoassay (e.g., ELISA, ImmunoCAP, or similar quantitative IgG antibody detection method)
CPT
86001
SNOMED
395143001
Specimen volume
1-2 mL of serum
Stability
Serum stable for 7 days at 2-8°C; for longer storage, freeze at -20°C or below
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–168 hours
Order
routine

Why Is This Test Done?

Your doctor may order a CRP test to check for signs of inflammation, monitor conditions like arthritis, infections, or heart disease, or evaluate responses to treatments. It can also help identify risks for certain health issues before symptoms appear.

What to Expect During the Test

A small blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The test is quick and doesn’t require special preparation.

What the Results Mean

Higher than normal levels of CRP may indicate inflammation, infections, or other health problems. Lower levels suggest minimal inflammation. Your doctor will interpret the results in the context of your overall health and medical history.

Common Conditions Monitored

CRP is often used to monitor conditions such as rheumatoid arthritis, lupus, heart disease, or to check for infections like pneumonia or sepsis. It can also help track how well treatments are working.

Reference range

Reference ranges vary by laboratory and methodology. Results are typically reported in mass/volume units (e.g., mg/L or μg/mL). Negative or low results generally indicate no significant sensitization. Consult laboratory-specific reference ranges for clinical interpretation.N/A

Specimen: serum

No special preparation required. Fasting is not necessary. Patient should be on a regular diet including suspected food items prior to testing for optimal sensitivity of IgG detection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a marker for inflammation and can signal underlying health issues. Elevated levels may prompt further testing or adjustments to treatment plans, while consistently low levels may indicate good overall health or effective management of conditions causing inflammation.

Short name

CRP (Serum/Plasma)

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections, injuries, autoimmune diseases, or certain medications. They may also fluctuate with stress, diet, or physical activity. Smoking or obesity can sometimes affect CRP levels too.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition and treatment plan. Some people may need it monthly, quarterly, or annually, depending on their needs.
Can lifestyle changes affect CRP levels?
Yes, lifestyle changes such as quitting smoking, improving diet, exercising regularly, and managing stress can help lower CRP levels and reduce inflammation in your body.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy