Anti-Borrelia burgdorferi IgG Antibody (Serum/Plasma) – Fluorescent Immunoassay

What This Test Measures

The test measures the presence of Immunoglobulin G (IgG) antibodies against *Borrelia burgdorferi* in your serum or plasma. These antibodies develop after your immune system has encountered the bacterium, typically within weeks to months after infection. The fluorescent immunoassay detects these antibodies by binding them to labeled probes, producing a measurable signal if antibodies are present.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like fever, rash (e.g., bull’s-eye rash), joint pain, or neurological issues (e.g., meningitis) that could suggest Lyme disease. It’s also used to confirm a diagnosis after initial testing or monitor treatment progress.

How It’s Done

A blood sample is drawn from a vein in your arm. The serum or plasma is then tested in a lab using fluorescent immunoassay, where antibodies bind to labeled antigens. A fluorescent signal indicates a positive result if antibodies are detected.

What the Results Mean

A positive result suggests past or current infection with *Borrelia burgdorferi*. However, false positives can occur, especially in people with other infections or autoimmune conditions. A negative result means no detectable antibodies were found, but it doesn’t rule out Lyme disease definitively if symptoms persist.